Unique ID issued by UMIN | UMIN000038833 |
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Receipt number | R000044284 |
Scientific Title | Effects of bicarbonate/lactate-buffered neutral peritoneal dialysis fluid on angiogenesis-related proteins in patients undergoing peritoneal dialysis |
Date of disclosure of the study information | 2019/12/09 |
Last modified on | 2019/12/09 22:34:33 |
Effects of bicarbonate/lactate-buffered neutral peritoneal dialysis fluid on angiogenesis-related proteins in patients undergoing peritoneal dialysis
Effects of bicarbonate/lactate-buffered neutral peritoneal dialysis fluid on angiogenesis-related proteins in patients undergoing peritoneal dialysis
Effects of bicarbonate/lactate-buffered neutral peritoneal dialysis fluid on angiogenesis-related proteins in patients undergoing peritoneal dialysis
Effects of bicarbonate/lactate-buffered neutral peritoneal dialysis fluid on angiogenesis-related proteins in patients undergoing peritoneal dialysis
Japan |
Chronic renal failure
Nephrology |
Others
NO
To evaluate the effects of bicarbonate/lactate-buffered neutral peritoneal dialysis fluid on the profile of angiogenesis-related proteins in drained dialysate of patients undergoing PD.
Safety,Efficacy
angiogenesis-related proteins in drained dialysate
Interventional
Cross-over
Non-randomized
Open -no one is blinded
Active
2
Treatment
Medicine |
patients were randomly allocated to sequential treatment with L-PDFs following B/L-PDFs(Group A, n=5) or vice versa (Group B, n=5)
patients were randomly allocated to sequential treatment with L-PDFs following B/L-PDFs(Group A, n=5) or vice versa (Group B, n=5
20 | years-old | <= |
90 | years-old | >= |
Male and Female
Patients with End-stage kidney disease undergoing peritoneal dialysis
Younger than 20 years old
Patients undergoing automated peritoneal dialysis.
Patients with peritonitis
10
1st name | Tetsu |
Middle name | |
Last name | Miyamoto |
University of Occupational and Environmental Health
Kidney Center
807-8555
Iseigaoka 1-1, Yahatanishi, Kitakyushu
093-603-1611
tetsum@med.uoeh-u.ac.jp
1st name | TETSU |
Middle name | MIYAMOTO |
Last name | MIYAMOTO |
University of Occupational and Environmental Health
Kidney Center
807-8555
1-1 Iseigaoka, Yahatanishi
0936031611
tetsum@med.uoeh-u.ac.jp
University of Occupational and Environmental Health
University of Occupational and Environmental Health
Other
University of Occupational and Environmental Health
Iseigaoka 1-1, Yahatanishi, Kitakyushu
093-603-1611
tetsum@med.uoeh-u.ac.jp
NO
2019 | Year | 12 | Month | 09 | Day |
in preparation
Unpublished
in preparation
10
In the 19 angiogenesis-related proteins investigated in this study, the expression of growth related oncogene (GRO, CXCL), which belongs to the CXC chemokine family, decreased significantly after use of the B/L-PDFs compared to the L-PDFs (P=0.04). Patients with short-term dialysis vintage tended to have lower levels of angiogenesis-related protein levels when using the B/L-PDFs (P=0.004).
2019 | Year | 12 | Month | 09 | Day |
Four Female, 52-78 yrs old, 4 DM patients
In 24 PD patients in our department, 14 patients with APD were excluded. 10 patients were enrolled and completed whole protocol.
None
In the 19 angiogenesis-related proteins investigated in this study, the expression of growth related oncogene (GRO, CXCL), which belongs to the CXC chemokine family, decreased significantly after use of the B/L-PDFs compared to the L-PDFs (P=0.04). Patients with short-term dialysis vintage tended to have lower levels of angiogenesis-related protein levels when using the B/L-PDFs (P=0.004).
Completed
2015 | Year | 04 | Month | 01 | Day |
2015 | Year | 05 | Month | 07 | Day |
2015 | Year | 05 | Month | 07 | Day |
2015 | Year | 10 | Month | 31 | Day |
2019 | Year | 12 | Month | 09 | Day |
2019 | Year | 12 | Month | 09 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000044284
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