UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000036068 |
|---|---|
| Receipt number | R000041086 |
| Scientific Title | Effect of amino acids intake before and after resistance exercise on skeletal muscle. |
| Date of disclosure of the study information | 2025/09/30 |
| Last modified on | 2021/09/13 14:56:02 |
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Basic information
Public title
Effect of amino acids intake before and after resistance exercise on skeletal muscle.
Acronym
Effect of amino acids intake before and after resistance exercise on skeletal muscle.
Scientific Title
Effect of amino acids intake before and after resistance exercise on skeletal muscle.
Scientific Title:Acronym
Effect of amino acids intake before and after resistance exercise on skeletal muscle.
Region
| Japan |
Condition
Condition
Healthy
Classification by specialty
| Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
To investigate the effect of amino acids intake before and after exercise on skeltal muscle.
Basic objectives2
Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Protein metabolism
Key secondary outcomes
Inflammatory response
Base
Study type
Interventional
Study design
Basic design
Parallel
Randomization
Randomized
Randomization unit
Individual
Blinding
Double blind -all involved are blinded
Control
Placebo
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
2
Purpose of intervention
Treatment
Type of intervention
| Food |
Interventions/Control_1
amino acids intake - exercise - amino acids intake
Interventions/Control_2
placebo intake - exercise - placebo intake
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 20 | years-old | <= |
Age-upper limit
| 40 | years-old | >= |
Gender
Male
Key inclusion criteria
1. A student who belongs to Ritsumeikan University.
2. A healthy male adult aged 20 to 40 years old.
3. A subject who can provide written informed consent
Key exclusion criteria
1. Any subject who has allergy to thetest food ingredients
2. Any subject who conducts resistance training habitually more than once a week
3. Any subject who consumes amino acids or proteins routinely
4. Any subject who has leg orthopedic disease
5. Any subject who is infected or suspected to be infected with B or C hepatitis virus
6. Any subject who has a history of cardiovascular diseases such as heart disease and hypertension
7. Any subject who is taking antithrombotic drugs (warfarin etc.)
8. Any subject who is considered as inappropriate for participating into the study at the judgment of principal investigator
Target sample size
12
Research contact person
Name of lead principal investigator
| 1st name | Satoshi |
| Middle name | |
| Last name | Fujita |
Organization
Ritsumeikan University
Division name
Department of Sport and Health Sciene
Zip code
525-0058
Address
1-1-1, Nojihigashi, Kusatsu-shi, Shiga
TEL
077-561-5229
safujita@fc.ritsumei.ac.jp
Public contact
Name of contact person
| 1st name | Naoko |
| Middle name | |
| Last name | Fujimura |
Organization
Ajinomoto Co., Inc.
Division name
Human health & nutrition group, Institute of food sciences & technologies
Zip code
210-0801
Address
1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi
TEL
044-223-4114
Homepage URL
naoko_fujimura@ajinomoto.com
Sponsor or person
Institute
Department of Sport and Health Sciene, Ritsumeikan University
Institute
Department
Personal name
Funding Source
Organization
Ajinomoto Co., Inc.
Organization
Division
Category of Funding Organization
Profit organization
Nationality of Funding Organization
Japan
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
BKC research office, Ritsumeikan University
Address
1-1-1, Nojihigashi, Kusatsu-shi, Shiga
Tel
077-599-4175
b-rinri@st.ritsumei.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2025 | Year | 09 | Month | 30 | Day |
Related information
URL releasing protocol
https://www.mdpi.com/2072-6643/12/8/2421
Publication of results
Published
Result
URL related to results and publications
https://www.mdpi.com/2072-6643/12/8/2421
Number of participants that the trial has enrolled
24
Results
Anabolic signals were significantly enhanced in amino acids group than in placebo group after resistance exercise.
Results date posted
| 2021 | Year | 09 | Month | 13 | Day |
Results Delayed
Results Delay Reason
Date of the first journal publication of results
| 2020 | Year | 08 | Month | 12 | Day |
Baseline Characteristics
Young healthy adults (AVE. 21.4 years)
Participant flow
Recruit-randomized-test conducted
Adverse events
Non
Outcome measures
Anabolic and catabolic signaling in skeletal muscle
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Completed
Date of protocol fixation
| 2019 | Year | 01 | Month | 31 | Day |
Date of IRB
| 2019 | Year | 02 | Month | 15 | Day |
Anticipated trial start date
| 2019 | Year | 02 | Month | 28 | Day |
Last follow-up date
| 2019 | Year | 07 | Month | 11 | Day |
Date of closure to data entry
Date trial data considered complete
| 2019 | Year | 07 | Month | 19 | Day |
Date analysis concluded
| 2019 | Year | 11 | Month | 19 | Day |
Other
Other related information
Management information
Registered date
| 2019 | Year | 03 | Month | 02 | Day |
Last modified on
| 2021 | Year | 09 | Month | 13 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000041086
