Unique ID issued by UMIN | UMIN000035580 |
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Receipt number | R000040542 |
Scientific Title | Prospective pharmacokinetic study of continuous-infusional 5-FU |
Date of disclosure of the study information | 2019/01/18 |
Last modified on | 2021/07/14 12:54:35 |
Prospective pharmacokinetic study of continuous-infusional 5-FU
Pharmacokinetic study of 5-FU
Prospective pharmacokinetic study of continuous-infusional 5-FU
Pharmacokinetic study of 5-FU
Japan |
Gastrointestinal Cancers
Gastroenterology |
Malignancy
NO
To determine inter-individual variability in pharmacokinetics of BSA based 5-FU continuous intravenous infusion.
Pharmacokinetics
Others
Others
Not applicable
Distribution of area under the time-concentration couve (AUC) of 5-FU
Correlation of AUC and 5-FU related adverse events.
Impact of patient characteristics on AUC.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1)Patients who are planned for treatment with modified de Gramont regimen (5-FU 400mg/m2 bolus + 2400mg/m2 div + leucovorin) including mFOLFOX6, FOLFIRI, FOLFIRINOX, 5-FU/LV
1)Uncontrolled diarrhea (Grade =>2)
60
1st name | Yusuke |
Middle name | |
Last name | Tanigawara |
Keio University, School of Medicine
Department of clinical pharmacokinetics and pharmacodynamics
1608582
35 Shinanomachi, Shinjuku-ku, Tokyo, Japan
03-5363-3847
tanigawara@a7.keio.jp
1st name | Chiyo |
Middle name | K. |
Last name | Imamura |
Keio University, School of Medicine
Department of clinical pharmacokinetics and pharmacodynamics
1608582
35 Shinanomachi, Shinjuku-ku, Tokyo, Japan
03-5363-3706
imamurack@z3.keio.jp
Keio University
Keio University
Other
Keio University School of Medicine
35 Shinanomachi, Shinjuku-ku, Tokyo, Japan
03-5363-3503
med-rinri-jimu@adst.keio.ac.jp
NO
国立がん研究センター中央病院(東京都)
慶應義塾大学病院(東京都)
2019 | Year | 01 | Month | 18 | Day |
Unpublished
Completed
2018 | Year | 10 | Month | 16 | Day |
2018 | Year | 12 | Month | 11 | Day |
2019 | Year | 01 | Month | 01 | Day |
2020 | Year | 01 | Month | 31 | Day |
Observational study
2019 | Year | 01 | Month | 18 | Day |
2021 | Year | 07 | Month | 14 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000040542
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