Unique ID issued by UMIN | UMIN000034678 |
---|---|
Receipt number | R000039533 |
Scientific Title | Gluten sensitivity among the patients with depression and the possibility of therapeutic effect of gluten free diet |
Date of disclosure of the study information | 2018/12/01 |
Last modified on | 2020/11/02 11:52:14 |
Gluten sensitivity among the patients with depression and the possibility of therapeutic effect of gluten free diet
Gluten sensitivity among the patients with depression and the possibility of therapeutic effect of gluten free diet
Gluten sensitivity among the patients with depression and the possibility of therapeutic effect of gluten free diet
Gluten sensitivity among the patients with depression and the possibility of therapeutic effect of gluten free diet
Japan |
depression
Psychiatry |
Others
NO
To clarify the gluten sensitivity and its relationships between symptoms , severity, and drugs responsibility among the patients with depression in Japan and effectiveness of gluten free diet for the depression patients with gluten sensitivity.
Others
To measure the antibody related to gluten sensitivity with the plasma obtained from the patients with depression.
To investigate the effectiveness of gluten free diet for the depression patients with gluten sensitivity, open trail with gluten free diet for two weeks is performed.
Confirmatory
Others
Not applicable
Assessment of gluten sensitivity is determined by the titer of tissue transglutaminase IgA antibody, the deamidated gliadin peptide IgA antibody, gliadin IgA antibody, gliadin IgGa nti body.
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Food |
gluten sensitive patients with depression have gluten free diet for two weeks. Patients whose symptoms are improved (Score decrease twenty percents or CGI-I score above three at two weeks) continue gluten free diet for eight weeks.
20 | years-old | <= |
70 | years-old | >= |
Male and Female
patient who met the criteria of depression in the DSM-5
patient who can understand the purpose of this study and be approved to participate by doctor
patient who can provide written informed consent
patient with remarkable excitement, violent action, self-injurious behavior
patient with social behavior
patinet who can't provide written informed consent
patient who have substance abuse or dependent
100
1st name | |
Middle name | |
Last name | Yamada Hisashi |
hyogo college of medicine
department of psychiatry
1-1, mukogawatyo, nisinomiya city, hyogo
0798-45-6051
hisa0820@hyo-med.ac.jp
1st name | |
Middle name | |
Last name | Yamada Hisashi |
hyogo college of medicine
department of psychiatry
1-1, mukogawatyo, nisinomiya city, hyogo
0798-45-6051
hisa0820@hyo-med.ac.jp
hyogo college of medicine department of psychiatry
hyogo college of medicine department of psychiatry
Other
NO
2018 | Year | 12 | Month | 01 | Day |
Unpublished
Completed
2018 | Year | 12 | Month | 01 | Day |
2018 | Year | 12 | Month | 01 | Day |
2018 | Year | 12 | Month | 01 | Day |
2020 | Year | 09 | Month | 30 | Day |
2020 | Year | 09 | Month | 30 | Day |
2018 | Year | 10 | Month | 29 | Day |
2020 | Year | 11 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000039533