Unique ID issued by UMIN | UMIN000034259 |
---|---|
Receipt number | R000039060 |
Scientific Title | Evaluation of cerebral circulation during cardiovascular surgery by laser speckle flowgraphy |
Date of disclosure of the study information | 2018/09/25 |
Last modified on | 2020/03/25 16:19:09 |
Evaluation of cerebral circulation during cardiovascular surgery by laser speckle flowgraphy
Cerebral microcirculation during cardiovascular surgery
Evaluation of cerebral circulation during cardiovascular surgery by laser speckle flowgraphy
Cerebral microcirculation during cardiovascular surgery
Japan |
cardiovascular surgery
Anesthesiology | Cardiovascular surgery |
Others
NO
The aim of this study was to assess ONH blood flow during cardiovascular surgery using LSFG and to evaluate its feasibility and usability as a neuromonitor.
Safety,Efficacy
Mean blur rate
hemodynamic parameter
Observational
18 | years-old | < |
100 | years-old | >= |
Male and Female
Scheduled cardiovascular surgery
Fundus or intracranial vessel diseases, glaucoma, severe cataract, and retinal disease
25
1st name | Hirotsugu |
Middle name | |
Last name | Kanda |
Asahikawa Medical University
Department of Anesthesiology and Critical Care Medicine
078-8510
Midorigaoka-higashi 2-1-1-1, Asahikawa, Hokkaido, 078-8510, Japan
0166-68-2583
h.kanda0629@nifty.com
1st name | Hirotsugu |
Middle name | |
Last name | Hirotsugu Kanda |
Asahikawa Medical University
Department of Anesthesiology and Critical Care Medicine
078-8510
Midorigaoka-higashi 2-1-1-1, Asahikawa, Hokkaido, 078-8510, Japan
0166-68-2583
h.kanda0629@nifty.com
Asahikawa Medical University
Grant-in-Aid for Young Scientists
Non profit foundation
Asahikawa Medical University Research Ethics Committee
Midorigaoka-higashi 2-1-1-1, Asahikawa, Hokkaido, 078-8510, Japan
0166-68-2297
pikaseika@jimu.asahikawa-med.ac.jp
NO
2018 | Year | 09 | Month | 25 | Day |
https://reader.elsevier.com/reader/sd/pii/S000349751831868X?token=8FA4DFD0094D32335726932B95129DDCC0
Published
https://reader.elsevier.com/reader/sd/pii/S000349751831868X?token=8FA4DFD0094D32335726932B95129DDCC0
28
In conclusion, no significant difference was observed in the cerebral circulation between RCP and simple circulatory arrest without adjunctive strategy under moderate hypothermia. In contrast, the cerebral circulation during SCP was significantly higher than simple circulatory arrest and RCP. These results suggest that cerebral microcirculation may not be adequate during RCP compared with SCP under moderate hypothermia.
2020 | Year | 03 | Month | 25 | Day |
Consecutive patients who underwent scheduled aorticarch repair for aneurysm
A total of 28 consecutive patients were enrolled. Preopera-tive magnetic resonance imaging and computed tomographic scans indicated atherosclerotic lesions in the internal carotid artery in 3 patients. One patient had change of operative procedure or SCP methods. As a result, 23 patients were analyzed.
none
In this study, changes in MBR and rSO2 were set as primary outcomes.
Completed
2015 | Year | 12 | Month | 01 | Day |
2015 | Year | 11 | Month | 25 | Day |
2016 | Year | 01 | Month | 01 | Day |
2018 | Year | 03 | Month | 15 | Day |
LSFG-NAVI was used to evaluate ONH blood flow as a measure of cerebral microcirculation. The details of the underlying principles of LSFG are described elsewhere. Briefly, LSFG allows for noninvasive quantitative and qualitative evaluation of ocular perfusion using the laser speckle phenomenon, which is an interference event observed when coherent light sources are scattered by a diffusing surface. In accordance with the moving erythrocytes in the target area, the structure of the speckle pattern, which appears under the illumination of laser irradiation, varies depending on the blood flow velocity. The mean blur rate (MBR; measured in arbitrary units; AU), calculated from variations in the blurring, is a quantitative index of the relative blood flow velocity. MBR images are acquired continuously at a rate of 30 frames per second for a 4-s time period and transferred to a computer file. The LSFG Analyzer software then synchronizes the captured MBR images for 4 s and averages the MBR over the 4-s duration to produce a color-coded MBR map of the ONH as a qualitative analysis. In addition, the software calculates the mean MBR of each cardiac cycle over 4 s throughout the ONH as a quantitative analysis. Data are shown as mean standard division.
2018 | Year | 09 | Month | 25 | Day |
2020 | Year | 03 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000039060