Unique ID issued by UMIN | UMIN000033998 |
---|---|
Receipt number | R000038770 |
Scientific Title | Significant Correlation between Renal 123I-Metaiodobenzylguanidine Scintigraphy and Muscle Sympathetic Nerve Activity in Patients with Heart Failure with Reduced Ejection Fraction |
Date of disclosure of the study information | 2018/09/03 |
Last modified on | 2020/03/05 09:22:33 |
Significant Correlation between Renal 123I-Metaiodobenzylguanidine Scintigraphy and Muscle Sympathetic Nerve Activity in Patients with Heart Failure with Reduced Ejection Fraction
Study of renal MIBG in HFrEF patients
Significant Correlation between Renal 123I-Metaiodobenzylguanidine Scintigraphy and Muscle Sympathetic Nerve Activity in Patients with Heart Failure with Reduced Ejection Fraction
Study of renal MIBG in HFrEF patients
Japan |
HFrEF
Cardiology |
Others
NO
In this study, we hypothesized that HFrEF patients whose sympathetic nerves and humoral factor interaction are accelerated by pressure overloading, the dynamics of 123I is more likely to be observed. We compared renal MIBG and sympathetic nerve parameters and heart function indicators and examined how renal MIBG is related to cardiac function and circulatory dynamics.
Pharmacokinetics
Exploratory
Pragmatic
Not applicable
MIBG,MSNA
Observational
20 | years-old | <= |
85 | years-old | > |
Male and Female
HFrEF was defined according to the guidelines of the Japanese Circulation Society 10 for diagnosis and treatment of acute and chronic heart failure as left ventricular ejection fraction less than 40%.
Patients with an estimated glomerular filtration rate of <50 ml/min/1.73 m2, morphological kidney abnormality, renal vascular stenosis, advanced lung disease, mental illness, or acute cardiovascular disease were excluded.
30
1st name | Yoshitaka |
Middle name | |
Last name | Okabe |
Kanazawa University
cardiology
920-0934
Kanazawa city Takaramachi
09056828475
yosi3305@yahoo.co.jp
1st name | Yoshitaka |
Middle name | |
Last name | Okabe |
Kanazawa University
cardiology
920-0934
Kanazawa city Takaramachi
0770223611
yosi3305@yahoo.co.jp
Kanazawa University
Kanazawa University
Japanese Governmental office
Kanazawa university hospital
Kanazawa city Takaramachi
09056828475
yosi3305@yahoo.co.jp
NO
2018 | Year | 09 | Month | 03 | Day |
Unpublished
Open public recruiting
2014 | Year | 04 | Month | 01 | Day |
2014 | Year | 08 | Month | 03 | Day |
2014 | Year | 08 | Month | 05 | Day |
2018 | Year | 03 | Month | 31 | Day |
I have finished observing 20 cases
2018 | Year | 09 | Month | 03 | Day |
2020 | Year | 03 | Month | 05 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000038770
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |