Unique ID issued by UMIN | UMIN000033584 |
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Receipt number | R000037811 |
Scientific Title | Effect of anti-histamine and oral corticosteroid for symptoms in oral food challenge |
Date of disclosure of the study information | 2018/08/02 |
Last modified on | 2021/02/01 18:39:25 |
Effect of anti-histamine and oral corticosteroid for symptoms in oral food challenge
Anti-histamine and oral corticosteroid for symptoms in OFC
Effect of anti-histamine and oral corticosteroid for symptoms in oral food challenge
Anti-histamine and oral corticosteroid for symptoms in OFC
Japan |
food allergy
Pediatrics |
Others
NO
Anti-histamine and oral corticosteroid medications are widely used to treat acute allergic reaction symptoms. However, the effectiveness of anti-histamine and oral corticosteroid on induced-symptoms during oral food challenge (OFC) has not been clarified. We previously reported oral corticosteroid may shorten the time length of abdominal symptoms.
The aim of this study is to clarify prospectively whether anti-histamine and/or oral corticosteroid could shorten the duration of abdominal pain by double blind randomized controlled trial.
Efficacy
Duration of abdominal pain (Assessed with Wong-Baker FACES Pain Rating Scale at least every 5 minutes)
- Additional treatment (antihistamine, corticosteroid, adrenaline, Inhaled beta2-agonists)
- Duration of other symptoms
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Active
YES
NO
Institution is not considered as adjustment factor.
YES
No need to know
3
Treatment
Medicine |
Anti-histamine only
Oral corticosteroid only
Both anti-histamine and oral corticosteroid
Not applicable |
Not applicable |
Male and Female
Patients
1) who underwent inpatient OFC
2) who are 5 years old or older
3) who have abdominal pain when diagnosed as positive in OFC.
Patients who require adrenaline administration in time of randomization.
80
1st name | Kyohei |
Middle name | |
Last name | Takahashi |
National Hospital Organizaion Sagamihara Hospital
Department of Pediatrics
2520315
Sakuradai 18-1, Minami-ward, Sagamihara city, Kanagawa pref., Japan
042-742-8311
kcrt@kcrt.net
1st name | Kyohei |
Middle name | |
Last name | Takahashi |
National Hospital Organizaion Sagamihara Hospital
Department of Pediatrics
2520315
Sakuradai 18-1, Minami-ward, Sagamihara city, Kanagawa pref., Japan
042-742-8311
kcrt@kcrt.net
Department of Pediatrics, National Hospital Organizaion Sagamihara Hospital
None
Other
Sagamihara National Hospital Ethical Committee
Sakuradai 18-1, Minami-ward, Sagamihara city, Kanagawa pref., Japan
042-742-8311
NoPublicEmailAddress@example.com
NO
独立行政法人国立病院機構相模原病院
2018 | Year | 08 | Month | 02 | Day |
Unpublished
Open public recruiting
2018 | Year | 07 | Month | 28 | Day |
2017 | Year | 07 | Month | 04 | Day |
2018 | Year | 08 | Month | 01 | Day |
2030 | Year | 12 | Month | 31 | Day |
2018 | Year | 08 | Month | 01 | Day |
2021 | Year | 02 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000037811
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