Unique ID issued by UMIN | UMIN000032551 |
---|---|
Receipt number | R000037126 |
Scientific Title | The prospective study about the detection of myocardial damage after radiotherapy using cardiac magnatic resonance imaging |
Date of disclosure of the study information | 2018/05/11 |
Last modified on | 2022/05/14 10:49:46 |
The prospective study about the detection of myocardial damage after radiotherapy using cardiac magnatic resonance imaging
The prospective study about radiation-induced myocardial damage using cardiac magnatic resonance imaging
The prospective study about the detection of myocardial damage after radiotherapy using cardiac magnatic resonance imaging
The prospective study about radiation-induced myocardial damage using cardiac magnatic resonance imaging
Japan |
Esophageal Cancer
Radiology |
Malignancy
NO
The aim of this study is
1. To clarify myocardial changes (fibrosis) after radiotherapy using cardiac MRI.
2. To make early detection of radiation-induced heart disease and to apply these results to the future radiation plan.
Efficacy
Confirm late gadolinium enhancement (myocardial fibrosis) corresponding to radiation field 6 months and 1.5 years after radiotherapy and evaluate the correlations between radiation dose and myocardial fibrosis.
Examine the relationships between the frequency of cardiac events and myocardial changes.
Evaluate the correlations between the results of other examinations such as electrocardiography and myocardial changes.
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Diagnosis
Device,equipment |
Between Janualy 2013 and June 2016, the subjects will undergo cardiac MRI before, 6 month after and 1.5 years after the completion of radiation therapy.
20 | years-old | <= |
75 | years-old | >= |
Male and Female
Cases in which there is a radical adaptation of irradiation and long-term survival could be expected.
Eastern Cooperative Oncology Group performance status, 0-1.
Normal kidney function (estimated glomerular filtration rate [eGFR] < 30 ml/min/1.73m2).
There is written consent of the patient.
Cases in which the myocardium was expected to be included in radiation field.
Other active malignancy at the start of our study.
History of mediastinal radiotherapy.
History of chemotherapy.
History of heart disease.
30
1st name | Rei |
Middle name | |
Last name | Umezawa |
Tohoku University Hospital
Department of Radiation Oncology
980-8574
1-1 Seiryo-machi, Aoba-ku, Sendai
022-717-7312
reirei513@hotmail.com
1st name | Rei |
Middle name | |
Last name | Umezawa |
Tohoku University Hospital
Department of Radiation Oncology
980-8574
1-1 Seiryo-machi, Aoba-ku, Sendai
022-717-7312
reirei513@hotmail.com
Department of Radiation Oncology, Tohoku University, Graduate School of Medicine
Japan Society for the Promotion of Science
Japanese Governmental office
Ethics Committee Tohoku University Hospital
1-1 Seiryo-machi, Aoba-ku, Sendai
022-728-4105
ec@rinri.hosp.tohoku.ac.jp
NO
2018 | Year | 05 | Month | 11 | Day |
Partially published
23
No longer recruiting
2012 | Year | 11 | Month | 22 | Day |
2012 | Year | 12 | Month | 07 | Day |
2013 | Year | 01 | Month | 01 | Day |
2022 | Year | 03 | Month | 31 | Day |
2018 | Year | 05 | Month | 11 | Day |
2022 | Year | 05 | Month | 14 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000037126