UMIN-CTR Clinical Trial

Basic information
Official scientific title of the study	The Clinical Study evaluating correlation between BNP (B-type natriuretic peptide) and NT-proBNP (N-terminal pro BNP)
Title of the study (Brief title)	The Clinical Study evaluating correlation between BNP and NT-proBNP
Region	Japan

Condition
Condition	Cardiovascular disease
Classification by specialty	Cardiology
Classification by malignancy	Others
Genomic information	NO

Objectives
Narrative objectives1	To elucidate correlation between BNP (B-type natriuretic peptide) and NT-proBNP (N-terminal pro BNP).
Basic objectives2	Others
Basic objectives -Others	Development of conversion equation.
Trial characteristics_1	Others
Trial characteristics_2	Others
Developmental phase	Not applicable

Assessment
Primary outcomes	BNP and NT-proBNP.
Key secondary outcomes	Clinical information (sex, age, height, body weight, blood pressure, heart rate, SAS, NYHA class, HF stage class, heart disease, echocardiogram, blood test, urine test, chest X-ray, electrocardiogram, drug allergy, past history, smoking, drinking, family history).

Base
Study type	Observational

Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment

Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10

Eligibility
Age-lower limit	20 years-old <=
Age-upper limit	Not applicable
Gender	Male and Female
Key inclusion criteria	All patients whose BNP and NT-proBNP were measured at Department of Cardiovascular Medicine, Tohoku University Hospital.
Key exclusion criteria	Patients who were judged to be not eligible in the present study by the physician in charge.
Target sample size	3000

Research contact person
Name of lead principal investigator	Yasuhiko Sakata
Organization	Tohoku University Graduate School of Medicine
Division name	Department of Cardiovascular Medicine
Address	1-1, Seiryomachi, Aoba-ku, Sendai, Japan
TEL	022(717)7153
Email	sakatayk@cardio.med.tohoku.ac.jp

Public contact
Name of contact person	Yasuhiko Sakata
Organization	Tohoku University Graduate School of Medicine
Division name	Department of Cardiovascular Medicine
Address	1-1, Seiryomachi, Aoba-ku, Sendai, Japan
TEL	022(717)7153
Homepage URL
Email	sakatayk@cardio.med.tohoku.ac.jp

Sponsor
Institute	Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Institute
Department

Funding Source
Organization	None
Organization
Division
Category of Funding Organization	Self funding
Nationality of Funding Organization

Other related organizations
Co-sponsor	None
Name of secondary funｄer(s)	None

Secondary IDs
Secondary IDs	NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW

Institutions
Institutions	東北大学（宮城県）

Other administrative information
Date of disclosure of the study information	2018 Year 04 Month 16 Day

Progress
Recruitment status	No longer recruiting
Date of protocol fixation	2016 Year 10 Month 26 Day
Anticipated trial start date	2017 Year 04 Month 01 Day
Last follow-up date	2017 Year 10 Month 31 Day
Date of closure to data entry
Date trial data considered complete
Date analysis concluded

Related information
URL releasing protocol
Publication of results	Unpublished
URL releasing results
Results
Other related information	Retrospective study. All adult patients whose BNP and NT-proBNP were measured at Department of Cardiovascular Medicine, Tohoku University Hospital between April 2017 and October 2017.

Management information
Registered date	2018 Year 04 Month 16 Day
Last modified on	2018 Year 04 Month 16 Day

Link to view the page
URL(English)	https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000036789