Unique ID issued by UMIN | UMIN000032120 |
---|---|
Receipt number | R000036644 |
Scientific Title | Exploratory study on the usefulness of functional MRI and Ophthalmic ultrasound to the diagnosis and prognostic prediction of prolonged consciousness disturbance |
Date of disclosure of the study information | 2018/05/01 |
Last modified on | 2024/10/08 17:24:50 |
Exploratory study on the usefulness of functional MRI and Ophthalmic ultrasound to the diagnosis and prognostic prediction of prolonged consciousness disturbance
Exploratory study on the usefulness of functional MRI and Ophthalmic ultrasound to the diagnosis and prognostic prediction of prolonged consciousness disturbance
Exploratory study on the usefulness of functional MRI and Ophthalmic ultrasound to the diagnosis and prognostic prediction of prolonged consciousness disturbance
Exploratory study on the usefulness of functional MRI and Ophthalmic ultrasound to the diagnosis and prognostic prediction of prolonged consciousness disturbance
Japan |
Patient diagnosed as impaired consciousness that prolonged 48 hours or more after entering intensive care unit (ICU)
Neurology | Anesthesiology | Emergency medicine |
Intensive care medicine |
Others
NO
To explore the usefulness of functional differential magnetic resonance imaging (fMRI) image inspection and ophthalmic ultrasonic examination as a differential diagnostic tool for prolonged consciousness disturbance or prognostic prediction index exploratory.
Efficacy
Exploratory
Neurological function as of 28th (CRS-R, GOS-E scoring value)
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Diagnosis
Device,equipment |
Neural image evaluation after 72 hours (whole brain activation fMRI, resting f MRI, diffusion weighted imaging method, three dimensional high definition anatomical imaging, cerebral reflux MRI) and ophthalmic ultrasound; optic nerve sheath diameter
18 | years-old | < |
Not applicable |
Male and Female
1) Patient who has consciousness disorder that prolongs more than 48 hours after entering ICU
2) Patients aged 20 years or older at the time of acquiring consent (regardless of gender)
3) After receiving sufficient explanation for the participation of this study, patients who obtained written agreement from the patient himself or a substitute
1) Patients who can not image MRI
2) Patients with traumatic brain injury
3) Patients during sedation drug administration
4) Women who may be pregnant or have a possibility of pregnancy
5) Women who are breastfeeding
6) In addition, patients who are deemed inappropriate as research subjects by research managers
40
1st name | |
Middle name | |
Last name | Takashi Ota |
Shonan Kamakura General Hospital
Anesthesiology
Kamakura city, Okamoto 1370-1, Kanagawa, Japan
0467-46-1717
otacchi@gmail.com
1st name | |
Middle name | |
Last name | Takashi Ota |
Shonan Kamakura General Hospital
Anesthesiology
Kamakura city, Okamoto 1370-1, Kanagawa, Japan
0467-46-1717
otacchi@gmail.com
Shonan Kamakura General Hospital
none
Self funding
NO
2018 | Year | 05 | Month | 01 | Day |
Unpublished
Terminated
2018 | Year | 02 | Month | 01 | Day |
2021 | Year | 05 | Month | 13 | Day |
2018 | Year | 05 | Month | 01 | Day |
2021 | Year | 05 | Month | 13 | Day |
2018 | Year | 04 | Month | 05 | Day |
2024 | Year | 10 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000036644