Unique ID issued by UMIN | UMIN000030828 |
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Receipt number | R000035188 |
Scientific Title | The preventive effect for new vertebral fractures of zoledronic acid and denosumab combined with vitamin D in patients with rheumatoid arthritis. |
Date of disclosure of the study information | 2018/01/15 |
Last modified on | 2018/01/15 22:59:45 |
The preventive effect for new vertebral fractures of zoledronic acid and denosumab combined with vitamin D in patients with rheumatoid arthritis.
EVIDENCE study
The preventive effect for new vertebral fractures of zoledronic acid and denosumab combined with vitamin D in patients with rheumatoid arthritis.
EVIDENCE study
Japan |
Rheumatoid Arthritis
Osteoporosis
Clinical immunology | Orthopedics |
Others
NO
To compare the incidence ratio of new vertebral fractures between zoledronic acid and denosumab combined with vitamin D in patients with rheumatoid arthritis.
Efficacy
the incidence ratio of new vertebral fractures after two years
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
2
Prevention
Medicine |
zoledronic acid
denosumab
20 | years-old | <= |
Not applicable |
Male and Female
1) Patients with rheumatoid arthritis who fulfill 2010 ACR/EULAR criteria
2) Patients fulfill the primary osteoporosis criteria in Japan
3) Aged 20 years or older
4) The patients who provided their informed consent to participate in the study
1) The patients with contraindication to denosumab and bisphosphonate
2) The patients who used zoledronic acid or denosumab previously
3) The patients who used teriparatide previously
4) The patients who are not included other intervention study
7) Those who are not approved to be eligible to this study by corresponding researcher
500
1st name | |
Middle name | |
Last name | Tadashi Okano |
Osaka City University Graduate School of Medicine
Orthopaedic Surgery
1-4-3 Asahi-machi, Abeno-ku, Osaka545-8585, Japan
06-6645-3851
ma1sa3ru@med.osaka-cu.ac.jp
1st name | |
Middle name | |
Last name | Tadashi Okano |
Osaka City University Graduate School of Medicine
Orthopaedic Surgery
1-4-3 Asahi-machi, Abeno-ku, Osaka545-8585, Japan
06-6645-3851
ma1sa3ru@med.osaka-cu.ac.jp
Osaka City University Graduate School of Medicine
Self funding
Self funding
NO
2018 | Year | 01 | Month | 15 | Day |
Unpublished
Open public recruiting
2017 | Year | 10 | Month | 30 | Day |
2018 | Year | 01 | Month | 15 | Day |
2018 | Year | 01 | Month | 15 | Day |
2018 | Year | 01 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000035188
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