Unique ID issued by UMIN | UMIN000030548 |
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Receipt number | R000034855 |
Scientific Title | Comparison of Dapagliflozin and Pioglitazone Effects on Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes: A Randomized,Open-Label, Active-Controlled Trial |
Date of disclosure of the study information | 2017/12/25 |
Last modified on | 2018/09/21 09:49:21 |
Comparison of Dapagliflozin and Pioglitazone Effects on Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes: A Randomized,Open-Label, Active-Controlled Trial
Comparison of Dapagliflozin and Pioglitazone Effects on NAFLD and NASH in Patients With Type 2 Diabetes: A Randomized Trial
Comparison of Dapagliflozin and Pioglitazone Effects on Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes: A Randomized,Open-Label, Active-Controlled Trial
Comparison of Dapagliflozin and Pioglitazone Effects on NAFLD and NASH in Patients With Type 2 Diabetes: A Randomized Trial
Japan |
type 2 diabetes mellitus, NAFLD, NASH
Hepato-biliary-pancreatic medicine | Endocrinology and Metabolism |
Others
NO
To compare the effects between dapagliflozin and pioglitazone on nonalcoholic fatty liver disease and nonalcoholic steatohepatitis in patients with type 2 diabetes
Safety,Efficacy
Confirmatory
Pragmatic
Not applicable
HbA1c, hepatic attenuation compared with spleen on CT scan imaging
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
2
Treatment
Medicine |
Dapagliflozin 5 mg/day, 104 weeks
Pioglitazone 15-30 mg/day, 104 weeks
20 | years-old | <= |
80 | years-old | >= |
Male and Female
HbA1c= or > 6.5%
Patients with diabetes complications
100
1st name | |
Middle name | |
Last name | Satoshi Mochida |
Saitama Medical University
Department of gastroenterology and hepatology
38 Morohongo, Moroyamamachi
049-276-1111
smochida@saitama-med.ac.jp
1st name | |
Middle name | |
Last name | Nobuaki Nakayama |
Saitama Medical University
Department of gastroenterology and hepatology
38 Morohongo, Moroyamamachi
049-276-1111
nobunaka@saitama-med.ac.jp
Saitama Medical University Hospital
Saitama Medical University
Self funding
NO
2017 | Year | 12 | Month | 25 | Day |
Unpublished
Completed
2015 | Year | 09 | Month | 14 | Day |
2015 | Year | 09 | Month | 14 | Day |
2017 | Year | 12 | Month | 24 | Day |
2018 | Year | 09 | Month | 21 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000034855
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