Unique ID issued by UMIN | UMIN000030049 |
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Receipt number | R000034314 |
Scientific Title | PET Imaging-Based Evaluaion of Hepaobiliary transport in Humans with [18F]PTV |
Date of disclosure of the study information | 2017/11/20 |
Last modified on | 2022/05/25 14:00:21 |
PET Imaging-Based Evaluaion of Hepaobiliary transport in Humans with [18F]PTV
PET study in Humans with [18F]PTV
PET Imaging-Based Evaluaion of Hepaobiliary transport in Humans with [18F]PTV
PET study in Humans with [18F]PTV
Japan |
Healthy adult
Hepato-biliary-pancreatic medicine |
Others
NO
To investigate hepatic uptake and subsequent canalicular efflux of [18F]PTV in healthy subjects.
Pharmacokinetics
Exploratory
Not applicable
Disribution of Radioacivity in human dbdominal region and blood after adminisration of [18F]PTV
metabolite analysis of human blood by TLC
Interventional
Cross-over
Randomized
Individual
Open -no one is blinded
No treatment
NO
NO
Institution is not considered as adjustment factor.
NO
No need to know
2
Treatment
Medicine |
This study includes PET scan for 2 times.
For the first visit, the participants take only water.
For the second visit, they take livalo with water.
20 | years-old | <= |
64 | years-old | >= |
Male
healhy male who can have PET scan for about 90 min and temporal blood sampling for about 15 points.
1.those who have compligating disordes of
severe cenral nervous system, liver, and kidney damage.
2.those who take hyperlipidemia treatment, tuberculosis drug and other treatments for target regions.
3.those who are claustrophobia.
4.those who are not suiable for this study assessed by medical docors judge
8
1st name | Yasuyoshi |
Middle name | |
Last name | Watanabe |
Osaka City Universiy / RIKEN Center for Biosystems Dynamics Research
Graduate School of Medicine
545-8585 / 650-0047
1-4-3, Asahi-machi, Abeno-ku, Osaka / 6-7-3, Minatojima-minamimachi, Chuo-ku, Kobe
078-304-7101
yywata@riken.jp
1st name | Emi |
Middle name | |
Last name | Yamano |
RIKEN Center for Biosystems Dynamics Research
Pathophysiological and Health Science Team
650-0047
6-7-3, Minatojima-minamimachi, Chuo-ku, Kobe
078-304-7124
emi.yamano@riken.jp
RIKEN Center for Biosystems Dynamics Research
TAKEDA science foundation
Non profit foundation
JAPAN
Osaka City University Department of Nuclear Medicine, Osaka City University Department of Physiology, RIKEN
Safety Center, RIKEN, Kobe
2-2-3,minatojimaminamimachi chuo-ku kobe-city
078-306-0111
siyaku@ml.riken.jp
YES
3849
The Ethics Committee of Osaka City University
大阪市立大学医学部附属病院 核医学科、大阪市立大学大学院医学研究科生理学第一
2017 | Year | 11 | Month | 20 | Day |
Unpublished
Completed
2017 | Year | 08 | Month | 31 | Day |
2017 | Year | 10 | Month | 04 | Day |
2017 | Year | 11 | Month | 08 | Day |
2020 | Year | 03 | Month | 31 | Day |
2020 | Year | 03 | Month | 31 | Day |
2021 | Year | 03 | Month | 31 | Day |
2022 | Year | 03 | Month | 31 | Day |
2017 | Year | 11 | Month | 20 | Day |
2022 | Year | 05 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000034314
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