Unique ID issued by UMIN | UMIN000028172 |
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Receipt number | R000032248 |
Scientific Title | Influence of large amount substitution fluid on electrolyte change |
Date of disclosure of the study information | 2017/07/11 |
Last modified on | 2017/09/12 10:23:20 |
Influence of large amount substitution fluid on electrolyte change
Influence of large amount substitution fluid on electrolyte change
Influence of large amount substitution fluid on electrolyte change
Influence of large amount substitution fluid on electrolyte change
Japan |
dialysis
Nephrology |
Others
NO
It is a well-known fact that it influences electrolytes such as calcium in the body depending on the composition of the dialysate. In particular, there are also documents that bicarbonate dialysate (Carbosta) has a composition greatly different from that of other dialysate and has a great influence on the electrolyte, which is effective in preventing blood pressure lowering. However, when hemodiafiltration is replenished with a large amount of dialysate, it is not clarified at this time what kind of influence the body's electrolyte will have. We also acknowledge reports that the rapid correction of acidosis has an adverse effect on lower limb swings. Therefore, we used three types of dialysate, Carbosta, Kindari and Linpak this time, and evaluate the change of electrolyte in the body by treatment condition with hemodiafiltration.
Efficacy
Blood ionized calcium
At the start of therapy, 2 hours after the start of treatment, and at the end of treatment, blood test and concentration measurement in dialysis effluent were conducted.
1. Blood ionized magnesium
2. Blood bicarbonate ion
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Other |
Dialysate and replacement fluid amount are changed.
The replacement liquid volume was 60 L and 84 L by the pre-dilution , 8 L and 16 L by the post-dilution.
20 | years-old | <= |
Not applicable |
Male and Female
Stable chronic maintenance dialysis patients
Patient with cancer
Patient with CRP where there is remarkable inflammation more than 2
The patient who uses blood catharsis except hemodialysis therapy or the hemodialysis filtration therapy together
During the pregnancy or the patient whom I am nursing
The patient who has a high disability in the liver, a heart, the lungs
18
1st name | |
Middle name | |
Last name | Yusaku Tanaka |
Kawashima Hospital
Clinical department of engineering
1-1-39 Kitasako, Tokusima, 770-8548, Japan
088-631-0110
tanakayusaku0724@gmail.com
1st name | |
Middle name | |
Last name | Yusaku Tanaka |
Kawashima Hospital
Clinical department of engineering
1-1-39 Kitasako, Tokusima, 770-8548, Japan
088-631-0110
tanakayusaku0724@gmail.com
Kawashima Hospital
None
Self funding
NO
2017 | Year | 07 | Month | 11 | Day |
Unpublished
Completed
2017 | Year | 06 | Month | 06 | Day |
2017 | Year | 07 | Month | 17 | Day |
2017 | Year | 08 | Month | 31 | Day |
2017 | Year | 07 | Month | 10 | Day |
2017 | Year | 09 | Month | 12 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000032248
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