Unique ID issued by UMIN | UMIN000028140 |
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Receipt number | R000032211 |
Scientific Title | The effect of n-3 unsaturated fatty acids supplementation on quadriceps muscle weakness after total knee arthroplasty. |
Date of disclosure of the study information | 2017/07/11 |
Last modified on | 2019/09/02 22:28:41 |
The effect of n-3 unsaturated fatty acids supplementation on quadriceps muscle weakness after total knee arthroplasty.
The effect of n-3 unsaturated fatty acids supplementation on quadriceps muscle weakness after total knee arthroplasty.
The effect of n-3 unsaturated fatty acids supplementation on quadriceps muscle weakness after total knee arthroplasty.
The effect of n-3 unsaturated fatty acids supplementation on quadriceps muscle weakness after total knee arthroplasty.
Japan |
Osteoarthritis of the knee
Rehabilitation medicine |
Others
NO
The purpose of this study is to clarify the effectiveness of n-3 unsaturated fatty acids in patients waiting for total knee arthroplasty.
Efficacy
The Primary outcome is quadriceps muscle strength. All patients included in the study are assessed 2 times: tests are performed 1 month before surgery and 4 days after surgery.
The secondary outcomes are oxidative stress, polyunsaturated fatty acid in serum, knee swelling, knee pain.
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
No treatment
2
Treatment
Food |
Intervention group take a daily supplements with n-3 unsaturated fatty acids(EPA645mg & DHA215mg) from 30 days prior to surgery.
none
60 | years-old | <= |
79 | years-old | >= |
Male and Female
1. Japanese males and females
2. between 60 and 79 years old
3. primary knee osteoarthritis
4. radiographic severity classified using Kellgren-Lawrence System was grade 3 to grade 4
1. patients with serious heart disease and diabetes
2. history of rheumatoid arthritis, neurological disease, and peripheral artery disease
3. patients who are taking Warfarin and n-3 unsaturated fatty acids supplements
4. smoker
5. patients with exercise habits
30
1st name | |
Middle name | |
Last name | Yusuke Kubo |
Kobori Orthopedic Clinic
Department of Rehabilitation Medicine
548-2 Nearaichou, Kita-ku, Hmamatsu City, Shizuoka
053-438-3133
yusuke.kubo11@gmail.com
1st name | |
Middle name | |
Last name | Yusuke Kubo |
Kobori Orthopedic Clinic
Department of Rehabilitation Medicine
548-2 Nearaichou, Kita-ku, Hmamatsu City, Shizuoka
053-438-3133
yusuke.kubo11@gmail.com
Kobori Orthopedic Clinic
Seirei Christopher University
Other
NO
2017 | Year | 07 | Month | 11 | Day |
Unpublished
Completed
2017 | Year | 07 | Month | 07 | Day |
2017 | Year | 06 | Month | 02 | Day |
2017 | Year | 07 | Month | 11 | Day |
2019 | Year | 08 | Month | 01 | Day |
2017 | Year | 07 | Month | 07 | Day |
2019 | Year | 09 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000032211
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