Unique ID issued by UMIN | UMIN000027558 |
---|---|
Receipt number | R000031498 |
Scientific Title | Multicenter observational study on the connection between sarcopenia and the curability of chemotherapy in advanced or recurrent colorectal cancer. |
Date of disclosure of the study information | 2017/05/31 |
Last modified on | 2019/07/12 11:08:29 |
Multicenter observational study on the connection between sarcopenia and the curability of chemotherapy in advanced or recurrent colorectal cancer.
Multicenter observational study on the connection between sarcopenia and the curability of chemotherapy in advanced or recurrent colorectal cancer.
Multicenter observational study on the connection between sarcopenia and the curability of chemotherapy in advanced or recurrent colorectal cancer.
Multicenter observational study on the connection between sarcopenia and the curability of chemotherapy in advanced or recurrent colorectal cancer.
Japan |
Colorectal Cancer
Gastroenterology | Gastrointestinal surgery |
Malignancy
NO
The aim is to investigate the correration of skeletal mass and fat tissue mass calculated by CT with Overall survival, Progression free survival, Response rate, Adverse event rate for the patients registered in KSCC0701, 0801, 0802, 0902, 1002, 1101 who had progressive or reccurent colorectal cancer.
Safety
The primary outcomes are Overall survival period, relapse free survival period, response rate, Adverse event rate. We are going to investigate the correration the sarcopenia, the rate of skeletal muscle loss and subcutaneous or visceral fat with the primary outcomes.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1. The patient is found to have colorectal cancer histopathologically.
2. The tumor is too progressive or reccurent and no resectable. It is judged by the attending doctor.
3. First line systemic chemotherapy is administered.
4. The patients registered in KSCC0701, 0801, 0802, 0902, 1002, 1101 have the image of CT before the start of chemotherapy and 60 to 120 days or 150 to 210 after chemotherapy.
It is the excluded case that is judged irreverent by the attending doctor.
249
1st name | Eiji |
Middle name | |
Last name | Oki |
Graduate School of Medical Sciences, Kyushu University
Department of Surgery and Science, Graduate School of Medical Sciences
812-8582
3-1-1 Maidashi, Higashi-ku, Fukuoka, Japan
092-409-3500
sanae.sakamoto@ks-cc.or.jp
1st name | KSCC |
Middle name | |
Last name | Research Secretariat |
Kyushu Study group of Clinical Cancer
KSCC Research Secretariat
812-8582
3-1-1 Maidashi, Higashi-ku, Fukuoka, Japan
092-409-3500
sanae.sakamoto@ks-cc.or.jp
Kyushu Study group of Clinical Cancer
Kyushu Study group of Clinical Cancer
Other
Kyushu University Ethics Review Board
3-1-1, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan
092-641-1151
byssien@jimu.kyushu-u.ac.jp
NO
九州大学病院(福岡県)
2017 | Year | 05 | Month | 31 | Day |
Published
249
Completed
2017 | Year | 05 | Month | 24 | Day |
2017 | Year | 08 | Month | 02 | Day |
2017 | Year | 05 | Month | 30 | Day |
2019 | Year | 03 | Month | 31 | Day |
Skeletal mass area of lower L3 level(m2), Visceral fat area(m2), Subcutaneous fat area(m2), Abdominal circumference(cm), skeletal mass index(SMI=skeletal mass area/Height2), Visceral fat area(VFA)/Subcutaneous fat area(SFA)
Patients' information
Age, Sex, Birth date, Registered number, Body mass index(BMI=Weight/Height2), Labo data(AST, ALT, ALP, Na, K, Alb, Cr, T.Bil, CEA, CA19-9, WBC, Neut, Plt, Hb)
Disease information of the patients'
Clinical stage before treatment, Location of the tumor, History of surgery for the colorectal cancer(Ope date, The histopathological diagnosis), History of the chemotherapy(Regimen, dose, period, Best overall response)
Treatment outcome
Response rate(RR), Progression free survival(PFS), Overall survival(OS), Adverse event rate
2017 | Year | 05 | Month | 31 | Day |
2019 | Year | 07 | Month | 12 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000031498