Unique ID issued by UMIN | UMIN000027192 |
---|---|
Receipt number | R000031160 |
Scientific Title | Evaluation of eye disorder induced by chemotherapy including S-1 |
Date of disclosure of the study information | 2017/06/24 |
Last modified on | 2024/11/23 14:53:34 |
Evaluation of eye disorder induced by chemotherapy including S-1
EyeDropS study(HGCSG1604)
Evaluation of eye disorder induced by chemotherapy including S-1
EyeDropS study(HGCSG1604)
Japan |
Gastrointestinal cancer
Gastroenterology | Hepato-biliary-pancreatic medicine | Ophthalmology |
Malignancy
NO
We conducted this prospective cohort study to confirm more precise analysis about S-1 induced Eye disorders incidence
Others
prospective cohort study
Others
Others
Not applicable
cumulative incidence of epiphora in periods from start of S-1 chemotherapy to 12 weeks after induction S-1
cumulative incidence of epiphora in overall S-1 chemotherapy periods, the time of outbreak and severity of epiphora, the situation of ophthalmological intervention, ophthalmological changes, risk factors of epiphora, and QOL
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1) Histologically confirmed carcinoma in GIC, including esophageal, gastric, colorectal, pancreatic, and biliary cancer.
2) Receives chemotherapy including S-1.
3) Age 20 years or older
4) Written informed consent.
1) Prior medication of S-1.
2) Continuing the eye drops treatment.
3) Scheduled to have an ophthalmic operation within six months.
4) Lachrymal duct obstruction or more than
three points of corner conjunctiva epithelium disorder score.
180
1st name | Yoshito |
Middle name | |
Last name | Komatsu |
Hokkaido University Hospital
Cancer Center
060-8648
Kita 14-jo, Nishi 5-chome, Kita-ku, Sapporo, Japan
+81-11-716-1161
ykomatsu@ac.cyberhome.ne.jp
1st name | Masataka |
Middle name | |
Last name | Yagisawa |
Hokkaido University Hospital
Cancer center
060-8648
Kita 14-jo, Nishi 5-chome, Kita-ku, Sapporo, Japan
+81-11-716-1161
yagisawa.m@hotmail.co.jp
Hokkaido Gastrointestinal Cancer Study Group: HGCSG
none
Self funding
Ethical Review Board for Life Science and Medical Research, Hokkaido University Hospital
Kita 14-jo, Nishi 5-chome, Kita-ku, Sapporo, Japan
011-706-7636
crjimu@huhp.hokudai.ac.jp
NO
2017 | Year | 06 | Month | 24 | Day |
Unpublished
Completed
2018 | Year | 01 | Month | 17 | Day |
2018 | Year | 03 | Month | 07 | Day |
2018 | Year | 05 | Month | 21 | Day |
2021 | Year | 11 | Month | 30 | Day |
Study design: Prospective observational study
2017 | Year | 04 | Month | 29 | Day |
2024 | Year | 11 | Month | 23 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000031160