UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000027021 |
|---|---|
| Receipt number | R000030977 |
| Scientific Title | The neural mechanisms of reminiscence therapy and their relation to aging |
| Date of disclosure of the study information | 2017/04/18 |
| Last modified on | 2018/04/18 15:24:53 |
* This page includes information on clinical trials registered in UMIN clinical trial registed system.
* We don't aim to advertise certain products or treatments
Basic information
Public title
The neural mechanisms of reminiscence therapy and their relation to aging
Acronym
The neural correlates of reminiscence therapy
Scientific Title
The neural mechanisms of reminiscence therapy and their relation to aging
Scientific Title:Acronym
The neural correlates of reminiscence therapy
Region
| Japan |
Condition
Condition
Dementia, Depression
Classification by specialty
| Adult |
Classification by malignancy
Others
Genomic information
NO
Objectives
Narrative objectives1
Reminiscence therapy is one of the psychotherapy known to have mood improving effect on the dementia and depressed subjects. However, the neural mechanisms underlying that effect remain unknown. The objectives of this study were to reveal 1) the neural correlates of mood improving effect, 2) the effect of emotional valence (positive or negative) at the time of experiencing on the neural correlates of reminiscence, and 3) the aging effect of these neural correlates.
Basic objectives2
Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
brain activity during reminiscing autobiographical memory acquired by functional MRI
Key secondary outcomes
Base
Study type
Interventional
Study design
Basic design
Single arm
Randomization
Non-randomized
Randomization unit
Blinding
Open -no one is blinded
Control
Self control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
1
Purpose of intervention
Treatment
Type of intervention
| Maneuver |
Interventions/Control_1
We'll perform emotional autobiographical memory reminiscence task during functional MRI scanning (around 1 hour).
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 18 | years-old | <= |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
young group: undergraduate and graduate student
older group: people who are over 65 years old
Key exclusion criteria
(1) people who have ferromagnetic items inside and surface of the body (such as pacemeker, aneurysm clip and tattoo), who are claustrophobic, and who are in pregnancy.
(2) people who have past and present medical history of psychiatric and neurological disorders
(3) people who are left-handedness
(4) people who are extreme myopia
(5) people who have auditory impairment
Target sample size
80
Research contact person
Name of lead principal investigator
| 1st name | |
| Middle name | |
| Last name | Motoaki Sugiura |
Organization
Tohoku University
Division name
Institute of Development, Aging and Cancer
Zip code
Address
4-1 Seiryo-machi, Aoba-ku, Sendai, Japan
TEL
022-717-8563
motoaki.sugiura.d6@tohoku.ac.jp
Public contact
Name of contact person
| 1st name | |
| Middle name | |
| Last name | Kentaro Oba |
Organization
Tohoku University
Division name
Institute of Development, Aging and Cancer
Zip code
Address
4-1 Seiryo-machi, Aoba-ku, Sendai, Japan
TEL
022-717-8563
Homepage URL
kentaro.oba.c6@tohoku.ac.jp
Sponsor or person
Institute
Tohoku University
Institute
Department
Personal name
Funding Source
Organization
Ministry of Education, Culture, Sports, Science and Technology
Organization
Division
Category of Funding Organization
Japanese Governmental office
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Address
Tel
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2017 | Year | 04 | Month | 18 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Open public recruiting
Date of protocol fixation
| 2017 | Year | 04 | Month | 14 | Day |
Date of IRB
Anticipated trial start date
| 2017 | Year | 05 | Month | 15 | Day |
Last follow-up date
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Management information
Registered date
| 2017 | Year | 04 | Month | 17 | Day |
Last modified on
| 2018 | Year | 04 | Month | 18 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000030977
| Research Plan | |
|---|---|
| Registered date | File name |
| Research case data specifications | |
|---|---|
| Registered date | File name |
| Research case data | |
|---|---|
| Registered date | File name |
