Unique ID issued by UMIN | UMIN000026885 |
---|---|
Receipt number | R000030843 |
Scientific Title | Synergy effect when probiotics and prebiotics eaten together |
Date of disclosure of the study information | 2017/04/30 |
Last modified on | 2018/08/21 12:10:18 |
Synergy effect when probiotics and prebiotics eaten together
Synergy effect when probiotics and prebiotics eaten together
Synergy effect when probiotics and prebiotics eaten together
Synergy effect when probiotics and prebiotics eaten together
Japan |
Constipation and intestinal dysbiosis
Gastroenterology |
Others
NO
To investigate the synergy effect when probiotics and prebiotics eaten together on stool frequency and intestinal microbiota in Japanese young women.
Efficacy
Confirmatory
Explanatory
Not applicable
change in stool frequency and intestinal microbiota after supplementation of test foods for 2 weeks
questionnaire survey about eating behavior and psychosomatic state
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
YES
NO
Institution is not considered as adjustment factor.
NO
Central registration
4
Treatment
Food |
intake of test food containing Bifidobacterium lactis HN019 1 billion, CFU/3.33mg, daily with 100ml water or milk for 2 weeks
intake of test food containing6.25g polydextrose daily with 100ml water or milk for 2 weeks
intake of test food containing Bifidobacterium lactis HN019 1 billion, CFU/3.33mg, daily and 6.25g polydextrose daily with 100ml water or milk for 2 weeks
intake of placebo food containing 6.25g dextrin daily with 100ml water or milk for 2 weeks
18 | years-old | <= |
Not applicable |
Female
1) age more than 18 years old at consent and must be an Otsuma Women's University student
2) subjects understand the study procedures and agree to participate in the study by giving informed consent prior to the study
1) has history of cardiovascular diseases, liver disease, kidney disease digestive tract disease, respiratory disease, diabetes
2) has history of malignant disease or now on chronic disease therapy
3) takes drugs to treat disease
4) has history of drug and food allergy
5) has continuous intake of dietary fiber supplement (dietary fiber rich foods made with seaweed, konjak, psyllium etc) or whole grain cereals(whole grain wheat, brown rice, barley)
6) Females who are pregnant or lactating, and who could become pregnant during test period.
7) has smoking habit
8) Subjects who are participating the other clinical tests. Subjects who participated within 1-month prior to the current study and/or who plan to participate the other clinical tests.
9) has history of drug addiction or in therapy for drug addiction
10) Subject whose stool frequency is more than 5 days weekly
11) is not appropriate in the investigator's opinion
28
1st name | |
Middle name | |
Last name | Seiichiro Aoe |
Otsuma Women's University
Fuculty of Home Economics
12 Sanban-cho, Chiyoda-ku, Tokyo 102-8357, Japan
03-5275-6048
s-aoe@otsuma.c.jp
1st name | |
Middle name | |
Last name | Hideki Sakanishi |
Danisco Japan Inc.
Nutrition and Health
Sanno Park Tower 11-1, Nagata-Cho 2-chome, Chiyoda-ku, 100-6111,Tokyo
03-5521-2427
Hideki.Sakanishi@dupont.com
Otsuma Wonmen'w University
Fuculty of Home Economics
Danisco Japan Inc.
Nutrition and Health
Profit organization
Japan
NO
大妻女子大学家政学部
2017 | Year | 04 | Month | 30 | Day |
Published
http://www.oatext.com/pdf/IMM-4-306.pdf
The intake of polydextrose for 2 weeks increased the proportion of fecal Bacteroides. The combined intake of probiotics and prebiotics may increase stool amounts via increasing the proportion of Bacteroides among
the fecal microbiota.
Completed
2016 | Year | 11 | Month | 30 | Day |
2016 | Year | 12 | Month | 04 | Day |
2017 | Year | 04 | Month | 10 | Day |
2017 | Year | 04 | Month | 14 | Day |
2017 | Year | 04 | Month | 25 | Day |
2017 | Year | 05 | Month | 25 | Day |
2017 | Year | 04 | Month | 06 | Day |
2018 | Year | 08 | Month | 21 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000030843