Unique ID issued by UMIN | UMIN000026442 |
---|---|
Receipt number | R000030380 |
Scientific Title | Effects of concomitant administration of DPP-4 and SGLT2 inhibitors in Japanese patients with type 2 diabetes |
Date of disclosure of the study information | 2017/03/07 |
Last modified on | 2017/03/07 16:12:26 |
Effects of concomitant administration of DPP-4 and SGLT2 inhibitors in Japanese patients with type 2 diabetes
Effects of concomitant administration of DPP-4 and SGLT2 inhibitors in Japanese patients with type 2 diabetes
Effects of concomitant administration of DPP-4 and SGLT2 inhibitors in Japanese patients with type 2 diabetes
Effects of concomitant administration of DPP-4 and SGLT2 inhibitors in Japanese patients with type 2 diabetes
Japan |
Type 2 diabetes
Endocrinology and Metabolism |
Others
NO
To evaluate effects of concomitant administration of DPP-4 and SGLT2 inhibitors on BMI, glycemic control, plasma lipids, and hepatic function in type 2 diabetic patients
Efficacy
Body mass index, HbA1c, plsma total cholesterol, HDL and LDL cholesterol, triglyceride, AST, ALT, and gamma-GTP levels at 6 months after the start of drug treatment
Plasma uric acid level at 6 months after the start of drug treatment
Interventional
Parallel
Non-randomized
Open -no one is blinded
Active
2
Treatment
Medicine |
Administration of SGLT2 inhibitor (luseogliflozin 2.5 mg q.d., dapagliflozin 5 mg q.d., tofogliflozin 20 mg q.d., empagliflozin 10 mg q.d., or canagliflozin 100 mg q.d.) for 6 months
Concomitant administration of SGLT2 inhibitor and DPP-4 inhibitor (sitagliptin 50 mg q.d., vildagliptin 50 mg b.i.d., alogliptin 25 mg q.d., anagliptin 100 mg b.i.d., or linagliptin 5 mg q.d.) for 6 months
30 | years-old | <= |
80 | years-old | > |
Male and Female
Type 2 diabetic patients.
Obtained written informed consent from the patients before participation.
Having severe nephropathy.
220
1st name | |
Middle name | |
Last name | Masataka Kusunoki |
Nagoya University
Research Center of Health, Physical Fitness and Sports
Furo-cho, Chikusa-ku, Nagoya
052-789-3946
info@tonyo.jp
1st name | |
Middle name | |
Last name | Masataka Kusunoki |
Nagoya University
Research Center of Health, Physical Fitness and Sports
Furo-cho, Chikusa-ku, Nagoya
052-789-3946
info@tonyo.jp
Nagoya University
Self funding
Self funding
NO
医療法人社団織田会あきしまクリニック(愛知県)
2017 | Year | 03 | Month | 07 | Day |
Unpublished
Completed
2015 | Year | 02 | Month | 02 | Day |
2015 | Year | 03 | Month | 02 | Day |
2016 | Year | 10 | Month | 27 | Day |
2016 | Year | 11 | Month | 04 | Day |
2016 | Year | 11 | Month | 29 | Day |
2016 | Year | 12 | Month | 11 | Day |
2017 | Year | 03 | Month | 07 | Day |
2017 | Year | 03 | Month | 07 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000030380