Unique ID issued by UMIN | UMIN000026380 |
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Receipt number | R000030298 |
Scientific Title | Monitoring kinetics of cytokines and growth factors before and after liver resection |
Date of disclosure of the study information | 2017/03/03 |
Last modified on | 2017/03/07 10:49:32 |
Monitoring kinetics of cytokines and growth factors before and after liver resection
Monitoring Kinetics of cytokines and growth factors before and after liver resection
Monitoring kinetics of cytokines and growth factors before and after liver resection
Monitoring Kinetics of cytokines and growth factors before and after liver resection
Japan |
Hepatocellular Carcinoma
Hepato-biliary-pancreatic surgery |
Malignancy
NO
Identify marker for Hepatocellular carcinoma recurrence after liver resection
Others
Identify marker for early recurrence of Hepatocellular carcinoma after liver resection
Exploratory
Pragmatic
Not applicable
Evaluating platelet-derived serotonin association with early (less than 2 years) and late (more than 2 years) Hepatocellular carcinoma recurrence after liver resection
Vascular endothelial growth factor-A, TNF, IL-6, Hepatocyte growth factor, Angiopoietin 1 and 2, Epidermal growth factor, soluble Vascular endothelial growth factor receptor 1 and 2, Insulin-like growth factor 1 and 2, TGF beta, Angiotensin-(1-7), ACE and ACE2, Platelet derived growth factor-BB
Others,meta-analysis etc
20 | years-old | <= |
Not applicable |
Male and Female
Hepatocellular carcinoma patients
who undergoes liver resection
Patients taking anti-platelet drugs,
platelet transfusion and psychosomatic medicines
100
1st name | |
Middle name | |
Last name | Yutaka Imoto |
Kagoshima University Graduate School of Medical and Dental Sciences
Cardiovascular and Gastroenterological surgery
8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan
099-275-5368
imotom3@kufm.kagoshima-u.ac.jp
1st name | |
Middle name | |
Last name | Toshiaki Shimizu |
Kagoshima University Graduate School of Medical and Dental Sciences
Laboratory and Vascular Medicine
8-35-1 Sakuragaoka, Kagoshima, 890-8520, Japan
099-275-5437
tshimizu@m.kufm.kagoshima-u.ac.jp
Cardiovascular and Gastroenterological surgery, Kagoshima University Graduate School of Medical and Dental Sciences
Research expenses of Laboratory and Vascular Medicine, Kagoshima University Graduate School of Medical and Dental Sciences
Other
NO
2017 | Year | 03 | Month | 03 | Day |
Unpublished
Enrolling by invitation
2013 | Year | 01 | Month | 31 | Day |
2013 | Year | 02 | Month | 01 | Day |
50 Hepatocellular carcinoma patients undergoing liver resection with informed consent to participate in the study is included. 50 healthy volunteers were also considered. Study period is from January 31, 2013 to January 31, 2018.
We evalute VEGF-A, TNF, IL-6, HGF, Ang-1 and -2, EGF, sVEGFR-1 and -2, IGF-1 and -2, TGF-beta, Angiotensin-(1-7), ACE and ACE2, and PDGF-BB in serum, plasma and intra-platelet.
2017 | Year | 03 | Month | 03 | Day |
2017 | Year | 03 | Month | 07 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000030298
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