Unique ID issued by UMIN | UMIN000024458 |
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Receipt number | R000027881 |
Scientific Title | Multicenter prospective single-group study of three-day regimen of oseltamivir (Tamiflu) for postexposure prophylaxis. |
Date of disclosure of the study information | 2016/10/31 |
Last modified on | 2023/10/23 14:30:24 |
Multicenter prospective single-group study of three-day regimen of oseltamivir (Tamiflu) for postexposure prophylaxis.
Three-day regimen of oseltamivir for postexposure prophylaxis.
Multicenter prospective single-group study of three-day regimen of oseltamivir (Tamiflu) for postexposure prophylaxis.
Three-day regimen of oseltamivir for postexposure prophylaxis.
Japan |
Individuals who shared a room with the index patient infected with influenza.
Infectious disease |
Others
NO
In this study, index patients who developed influenza during hospitalization were transferred to isolation rooms, and individuals who shared a room with the index patient are administered oseltamivir for three
days as postexposure prophylaxis. The aim of this study is to analyse the effectiveness of a three-day regimen of oseltamivir.
Efficacy
Primary outcome of this study is occurrence of influenza infection after a three-day regimen of oseltamivir as postexposure prophylaxis. Individuals who shared a room with the index patient infected with influenza were monitored for influenza-like symptoms for seven days after postexposure prophylaxis.
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Prevention
Medicine |
Individuals who shared a room with the influenza patient with a positive immuno-chromatographic test were given oseltamivir for three days as post-exposure prophylaxis.
1 | years-old | <= |
Not applicable |
Male and Female
1. Patiets older than one year of age.
2. Individuals who shared a room with influenza patient (index case) with a positive immuno-chromatographic test were immediately separated from the index case by transferring to isolation room.
3. Oseltamivir for post-exposure prophylaxis was started within 48 hours after the onset of fever in the index case.
4. Written informed consent was obtained from each patient before enrolment.
1. Patients with renal insufficiency (creatinine clearance less than 30 mL/min).
2. Patients older than 10 years and younger than 20 years.
3. Any other patients who are regarded as unsuitable for this study by the investigator.
279
1st name | Nobuhisa |
Middle name | |
Last name | Ishiguro |
Hokkaido University Hospital
Infection Control Team
060-8648
Kita-14, Nishi-5, Kita-ku, Sapporo
011-706-5703
nishigur@med.hokudai.ac.jp
1st name | Nobuhisa |
Middle name | |
Last name | Ishiguro |
Hokkaido University Hospital
Infection Control Team
060-8648
Kita-14, Nishi-5, Kita-ku, Sapporo
011-706-5703
nishigur@med.hokudai.ac.jp
Hokkaido University
Hokkaido University
Government offices of other countries
Hokkaido University Certified Review Board
Kita-14, Nishi-5, Kita-ku, Sapporo
011-706-7934
recjimu@huhp.hokudai.ac.jp
NO
2016 | Year | 10 | Month | 31 | Day |
Unpublished
Open public recruiting
2016 | Year | 09 | Month | 08 | Day |
2016 | Year | 11 | Month | 11 | Day |
2016 | Year | 11 | Month | 09 | Day |
2026 | Year | 03 | Month | 31 | Day |
2016 | Year | 10 | Month | 18 | Day |
2023 | Year | 10 | Month | 23 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000027881
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