Unique ID issued by UMIN | UMIN000024137 |
---|---|
Receipt number | R000027794 |
Scientific Title | Phase II study of combination chemotherapy using paclitaxel, carboplatin, and bevacizumab in patients with advanced or recurrent cervical cancer. |
Date of disclosure of the study information | 2016/09/23 |
Last modified on | 2016/09/23 15:03:20 |
Phase II study of combination chemotherapy using paclitaxel, carboplatin, and bevacizumab in patients with advanced or recurrent cervical cancer.
CC-Bev
Phase II study of combination chemotherapy using paclitaxel, carboplatin, and bevacizumab in patients with advanced or recurrent cervical cancer.
CC-Bev
Japan |
cervical cancer
Obstetrics and Gynecology |
Malignancy
NO
To assess the efficacy of combination chemotherapy using paclitaxel, carboplatin, and bevacizumab (TC+Bev therapy).
Safety
Exploratory
Explanatory
Phase II
Objective response rate
Overall survival, Progression free survival, Toxicity
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Paclitaxel 175mg/m2
Carboplatin AUC =6
Bevacizumab 15mg/kg
Q 3 weeks
20 | years-old | <= |
Not applicable |
Female
1. Histologically proven cervical cancer.
2. FIGO stage IVb or recurrent cervical cancer. Previous one or two regimens of chemotherapy is permitted.
3. Patient with assessable tumor.
4. ECOG PS: 0 to 2.
1. Previous paclitaxel or carboplatin administration within 6 months of registration.
2. Any active concomitant malignancy.
3. Severe comorbidity.
30
1st name | |
Middle name | |
Last name | Shoji Nagao |
Hyogo Cancer Center
Gynecologic Oncology
13-70Kitaoji-cho, Akashi-city
078-929-1151
nagao@hp.pref.hyogo.jp
1st name | |
Middle name | |
Last name | Shoji Nagao |
Hyogo Cancer Center
Gynecologic Oncology
13-70Kitaoji-cho, Akashi-city
078-929-1151
nagao@hp.pref.hyogo.jp
Hyogo Cancer Center
None
Other
NO
2016 | Year | 09 | Month | 23 | Day |
Unpublished
Open public recruiting
2016 | Year | 06 | Month | 14 | Day |
2016 | Year | 07 | Month | 15 | Day |
2016 | Year | 09 | Month | 23 | Day |
2016 | Year | 09 | Month | 23 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000027794