Unique ID issued by UMIN | UMIN000023857 |
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Receipt number | R000027430 |
Scientific Title | A randamized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy of yogurt containing probiotic LKM512 and arginine on function of vascular endothelium and intestinal environment |
Date of disclosure of the study information | 2016/08/31 |
Last modified on | 2019/06/11 18:47:50 |
A randamized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy of yogurt containing probiotic LKM512 and arginine on function of vascular endothelium and intestinal environment
Effects of yogurt containing probiotic LKM512 and arginine on function of vascular endothelium
A randamized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy of yogurt containing probiotic LKM512 and arginine on function of vascular endothelium and intestinal environment
Effects of yogurt containing probiotic LKM512 and arginine on function of vascular endothelium
Japan |
Healthy adults
Adult |
Others
NO
To evaluate the efficacy of yogurt containing probiotic LKM512 and arginine on function of vascular endothelium in healthy adults
Safety,Efficacy
RH-PAT(Endo-PAT)
Blood biomarker, BMI, Systolic blood pressure, Diastolic blood pressure, Abdominal girth, Analyses of fecal samples
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
2
Prevention
Food |
The volunteer were given a 12-week treatment with 100g yogurt containing bifidobacteria LKM512 (10 billion bacterial cells/100g) and arginine (600mg/100g) once a day.
The volunteer were given a 12-week treatment with 100g yogurt without bifidobacteria LKM512 and arginine once a day.
30 | years-old | <= |
65 | years-old | >= |
Male and Female
The individuals whose BMl is under 30
1. Subjects who take a medicine, or visit the hospital for some disease
2. Subjects who had serious gastrointestinal disease, and subjects who had surgery of the digestive tract in the past
3. Subjects who was enrolled in other trails within one month, and female subjects who are, might become pregnant, or lactating
4. Subjects who have food allergies
5. Inappropriate cases evaluated by doctors
40
1st name | |
Middle name | |
Last name | Mitsuharu Matsumoto |
Kyodo Milk Industry Co. Ltd.
Research Laboratories
20-1 Hirai, Hinode-machi, Nishitama-gun, Tokyo 190-0182
042-597-5911
m-matumoto@meito.co.jp
1st name | |
Middle name | |
Last name | Satoshi Sakurai |
imeQ CO. Ltd.
CRO division
a vous primus Bld, 2-14-6, nishiwaseda, Shinjuku-ku, Tokyo 169-0075
03-6205-6222
s-sakurai@imeq.co.jp
Kyodo Milk Industry Co. Ltd.
Kyodo Milk Industry Co. Ltd.
Profit organization
NO
医療法人社団 札幌百合の会病院 (北海道)
2016 | Year | 08 | Month | 31 | Day |
Unpublished
Completed
2016 | Year | 08 | Month | 26 | Day |
2016 | Year | 08 | Month | 29 | Day |
2016 | Year | 09 | Month | 05 | Day |
2016 | Year | 12 | Month | 29 | Day |
2017 | Year | 02 | Month | 24 | Day |
2016 | Year | 08 | Month | 31 | Day |
2019 | Year | 06 | Month | 11 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000027430
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