Unique ID issued by UMIN | UMIN000023515 |
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Receipt number | R000027075 |
Scientific Title | A combination therapy of Ramucirumab and Paclitazel as second-line treatment for elderly gastric cancer patients: A exploratory phase II research |
Date of disclosure of the study information | 2016/12/01 |
Last modified on | 2020/08/20 15:30:31 |
A combination therapy of Ramucirumab and Paclitazel as second-line treatment for elderly gastric cancer patients: A exploratory phase II research
A combination therapy of Ramucirumab and Paclitazel for elderly gastric cancer patients
A combination therapy of Ramucirumab and Paclitazel as second-line treatment for elderly gastric cancer patients: A exploratory phase II research
A combination therapy of Ramucirumab and Paclitazel for elderly gastric cancer patients
Japan |
advanced gastric cancer
Gastrointestinal surgery |
Malignancy
NO
To clarify the feasibility of combination therapy of ramucirumab and paclitaxel as second-line treatment for elderly patients with advanced gastric cancer
Safety,Efficacy
Exploratory
Pragmatic
Phase II
Toxicity
Response rate, PFS, OS
Observational
75 | years-old | <= |
85 | years-old | > |
Male and Female
1. Histrogically proven adenocarcinoma
2. Advanced gastric cancer
3. Failure after first-line treatment
4. No massive ascites
5. No cerebrovascular disease
6. Possible oral intake
7. PS: 0 or 1
8. No lethal disfunction of the major organs
9. who gave informed consent
1. Unconrollable DM
2. VTE
3. MoI
4. Cerebrovascular disease
5. No GI tract bleeding or perforation
6. Uncontrollable hypertension
7. Inappropriate patient for study
35
1st name | Chikara |
Middle name | |
Last name | Kunisaki |
Medical Center, Yokohama City University
Dept. of Surg., Gastroenterological Center
232-0024
4-57, Urafune-cho, Minami-ku, Yokohama
045-261-5656
s0714@med.yokohama-cu.ac.jp
1st name | Chikara |
Middle name | |
Last name | Kunisaki |
Medical Center, Yokohama City University
Dept. of Surg., Gastroenterological Center
232-0024
4-57, Urafune-cho, Minami-ku, Yokohama
045-261-5656
s0714@med.yokohama-cu.ac.jp
Dept. of Surg., Gastroenterological Center, Medical Center, Yokohama City University
Yokohama City University
Other
Y-NEXT
1-1-1 Fukuura, Kanazawa-ku, Yokohama
0453707627
rinri@yokohama-cu.ac.jp
NO
2016 | Year | 12 | Month | 01 | Day |
Unpublished
Preinitiation
2016 | Year | 07 | Month | 14 | Day |
2016 | Year | 08 | Month | 08 | Day |
2020 | Year | 03 | Month | 31 | Day |
The protcol will be continued until PD or uncontrollable toxicity will be confirmed. Subsequently, the feasibility will be confirmed.
2016 | Year | 08 | Month | 06 | Day |
2020 | Year | 08 | Month | 20 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000027075
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