Unique ID issued by UMIN | UMIN000023175 |
---|---|
Receipt number | R000026716 |
Scientific Title | Preventive effect of a dentifrice containing three kinds of bactericidal ingredients in periodontal patients : a clinical study |
Date of disclosure of the study information | 2017/04/01 |
Last modified on | 2019/01/15 09:06:10 |
Preventive effect of a dentifrice containing three kinds of bactericidal ingredients in periodontal patients : a clinical study
Effectiveness of a dentifrice containing three kinds of bactericidal ingredients
Preventive effect of a dentifrice containing three kinds of bactericidal ingredients in periodontal patients : a clinical study
Effectiveness of a dentifrice containing three kinds of bactericidal ingredients
Japan |
Periodontal disease
Dental medicine | Adult |
Others
NO
The effects of a dentifrice which contains three kinds of bactericidal ingredients on periodontal disease are assessed in patients undergoing SPT.
Inflammatory markers of gingival crevicular fluid (GCF) and the presense of periodontopathic bacteria (5 species) in saliva are also assessed.
Efficacy
Exploratory
Others
Not applicable
Probing depth
Clinical attachment level
Plaque Index
Gingival Index
Gingival swelling
Gingival redness
Inflammatory markers of gingival crevicular fluid (GCF)
Periodontal pathogens
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Treatment
Other |
Brushing with a dentifrice (OC1510) offered to participants for 28 days.
20 | years-old | <= |
70 | years-old | >= |
Male and Female
1. Those who agreed to participate in the study with written informed consent.
2. The SPT patients with mild to moderate periodontitis at least one site with PD >=4 mm and GI1 or GI2.
1. Those with uncontrolled systemic diseases (ex. diabetes, hyperlipidemia, cardiovascular diseases, osteoporosis, autoimmune diseases)
2. Those with severe dental problems not suitable for this study
3. Those under periodontal therapy
4. Smokers
5. History of antimicrobial treatment or taking dietary supplements within 3 months
6. Those who received SRP within 3 months
7. Those who are already using a similar to present investigational dentifrice
8. Those who are judged as inappropriate by an attending dentist
30
1st name | |
Middle name | |
Last name | Takashi Kinumatsu |
Tokyo Dental College
Department of Periodontology
2-9-18 Misaki-cho, Chiyoda-ku, Tokyo 1010061 Japan
03-6380-9172
kinumatu@tdc.ac.jp
1st name | |
Middle name | |
Last name | Takashi Kinumatsu |
Tokyo Dental College
Department of Periodontology
2-9-18 Misaki-cho, Chiyoda-ku, Tokyo 1010061 Japan
03-6380-9172
kinumatu@tdc.ac.jp
Department of Periodontology, Tokyo Dental College
Daiichi Sankyo Healthcare Co., Ltd.
Profit organization
Japan
NO
東京歯科大学千葉病院(千葉県) Tokyo Dental College Chiba hospital
(Chiba)
東京歯科大学水道橋病院(東京都) Tokyo Dental College Suidobashi
Hospital(Tokyo)
2017 | Year | 04 | Month | 01 | Day |
Published
https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-018-3216-x
Completed
2016 | Year | 07 | Month | 12 | Day |
2016 | Year | 07 | Month | 20 | Day |
2016 | Year | 07 | Month | 14 | Day |
2019 | Year | 01 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000026716