Unique ID issued by UMIN | UMIN000023681 |
---|---|
Receipt number | R000026561 |
Scientific Title | Evaluation of efficiency and safety of dapagliflozin in treating of type 2 diabetes mellitus |
Date of disclosure of the study information | 2016/08/20 |
Last modified on | 2019/02/24 14:45:49 |
Evaluation of efficiency and safety of dapagliflozin in treating of type 2 diabetes mellitus
Efficiency and safety of dapagliflozin
Evaluation of efficiency and safety of dapagliflozin in treating of type 2 diabetes mellitus
Efficiency and safety of dapagliflozin
Japan |
type 2 diabetes
Endocrinology and Metabolism |
Others
NO
To examine the effect of the improvement of blood glucose levels and safety by dapagliflozin
Safety,Efficacy
Amount of change in HbA1c after administration 24 weeks later
Body weight
Blood pressure
Serum lipid
heart function (LVEF, E/A, E/e', DcT, LVMI,LAV)
Urinary albumin excretion
Urinary L-FABP excretion, serum cystatinC,eGFR
Liver function(AST,ALT,gammaGTP)
Observational
20 | years-old | <= |
75 | years-old | > |
Male and Female
Men and women who were diagnosed with type 2 diabetes mellitus.
Patients who are considered treatment with dapagliflozin is suitable.
Patients with hypertention and/or abnormal electrocardiographic pattern.
eGFR 45 ml/min/1.73 m2 <=
1.Type 1 diabetes mellitus
2.Diabetic ketoacidosis, diabetic coma, or before coma
3.Sever infection, before and not long after surgery, or patients with sever trauma
4.Left ventricular dysfunction (EF < 50%)
5.Sever liver dysfunction
6.Past history of cerebral infarction, myocardial infarction, and sever heart failure
7.Women suspected of pregnancy or pregnant
8.Patients with a history of use SGLT2 inhibitors
9.Patients who have repeated urinary tract infections
10.Alchole intake excessive
11.Inadequate patients judged by doctor
30
1st name | |
Middle name | |
Last name | Hajime M. Koyano |
Juntendo University Urayasu Hospital
Endocrinology and Diabetes
2-1-1 Tomioka, Urayasu-city, Chiba, Japan
047-353-3111
koyano@juntendo-urayasu.jp
1st name | |
Middle name | |
Last name | Hajime M. Koyano |
Juntendo University Urayasu Hospital
Endocrinology and Diabetes
2-1-1 Tomioka, Urayasu-city, Chiba, Japan
047-353-3111
koyano@juntendo-urayasu.jp
Juntendo University Urayasu Hospital
none
Self funding
NO
順天堂大学医学部附属浦安病院(千葉県)
2016 | Year | 08 | Month | 20 | Day |
Unpublished
No longer recruiting
2016 | Year | 08 | Month | 01 | Day |
2016 | Year | 08 | Month | 20 | Day |
We clarify the effect of the improvement of blood glucose levels and safety by dapagliflozin.
2016 | Year | 08 | Month | 19 | Day |
2019 | Year | 02 | Month | 24 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000026561