Unique ID issued by UMIN | UMIN000023045 |
---|---|
Receipt number | R000026534 |
Scientific Title | The effect of landiolol hydrochloride for primary lung cancer patients with tachyarrhythmia in the perioperative period |
Date of disclosure of the study information | 2016/07/06 |
Last modified on | 2020/01/08 09:30:08 |
The effect of landiolol hydrochloride for primary lung cancer patients with tachyarrhythmia in the perioperative period
The effect of landiolol hydrochloride for primary lung cancer patients with tachyarrhythmia in the perioperative period
The effect of landiolol hydrochloride for primary lung cancer patients with tachyarrhythmia in the perioperative period
The effect of landiolol hydrochloride for primary lung cancer patients with tachyarrhythmia in the perioperative period
Japan |
Primary lung cancer
Chest surgery |
Malignancy
NO
To investigate the shortening of administration of landiolol hydrochloride will suppress the perioperative of primary lung cancer patients with tachyarrhythmia
Safety,Efficacy
To compare the tachyarrhythmia incidence up to postoperative 72 hours between landiolol hydrochloride administration group and the non-administration group
Interventional
Single arm
Non-randomized
Open -no one is blinded
Historical
1
Prevention
Medicine |
The landiolol hydrochloride of 0.005mg/kg/min is administered to a patient through a indwelling aortic catheter from commencing surgery to postoperative day1 with adjusting the landiolol hydrochloride administration rate according to maintain the heart rate 60 (to 80) times/ min (dose titration method)
70 | years-old | <= |
Not applicable |
Male and Female
Including primary lung cancer patients who meet any one following conditions, a cardiac disease, bilobectomy with thoracotomy, lung resection with a bronchial formation or angiogenesis, lung resection with composite resection of organ around lung.
Patient corresponding to the contraindication of landiolol hydrochloride
1) Patients with cardiogenic shock
2) Patients with diabetic ketoacidosis or metabolic acidosis
3) Patients with auriculoventricular block(out of 2nd degree) or bradyarrhythmia including sick sinus syndrome
4)Patients with right cardiac failure from pulmonary hypertension
5) Patients with congestive cardiac failure
6) Patients with untreated phaeochromocytoma
7) Patients with a previous history of hypersensitivity to components of landiolol hydrochloride
8) Patients with bronchial asthma
9) Patient with sick sinus syndrome(Including a pacemaker implantation)
10) Patient who is pregnant woman also possibility of pregnancy or nursing mother
11) Patient who is judged as inappropriate by doctor in attendance
50
1st name | Yukitoshi |
Middle name | |
Last name | Satoh |
Kitasato University School of Medicine
Department of Thoracic Surgery
252-0374
1-15-1 Kitasato, Minami-ku, Sagamihara-shi, Kanagawa, 252-0374, Japan
042-778-8828
ysatoh@med.kitasato-u.ac.jp
1st name | Yukitoshi |
Middle name | |
Last name | Satoh |
Kitasato University School of Medicine
Department of Thoracic Surgery
252-0374
1-15-1 Kitasato, Minami-ku, Sagamihara-shi, Kanagawa, 252-0374, Japan
042-778-8828
ysatoh@med.kitasato-u.ac.jp
Department of Thoracic Surgery, Kitasato University
Kitasato University School of Medicine
Self funding
Kitasato University Medical Ethics Organization
1-15-1 Minami-ku Sagamihara Kanagawa
042-778-8273
rinri-n@kitasato-u.ac.jp
NO
2016 | Year | 07 | Month | 06 | Day |
Unpublished
Completed
2013 | Year | 12 | Month | 11 | Day |
2013 | Year | 12 | Month | 11 | Day |
2016 | Year | 07 | Month | 05 | Day |
2019 | Year | 03 | Month | 29 | Day |
2016 | Year | 07 | Month | 06 | Day |
2020 | Year | 01 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000026534
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |