Unique ID issued by UMIN | UMIN000021792 |
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Receipt number | R000025134 |
Scientific Title | Examination of the relationship between Alzheimer's disease and arteriosclerosis |
Date of disclosure of the study information | 2016/04/07 |
Last modified on | 2018/04/09 07:14:41 |
Examination of the relationship between Alzheimer's disease and arteriosclerosis
Examination of the relationship between Alzheimer's disease and arteriosclerosis
Examination of the relationship between Alzheimer's disease and arteriosclerosis
Examination of the relationship between Alzheimer's disease and arteriosclerosis
Japan |
Alzheimer's disease, Mild cognitive impairment, Elderly persons without cognitive impairment
Neurology | Geriatrics | Psychiatry |
Others
NO
Alzheimer's disease often have arteriosclerosis. The aim of this study is to investigate the relationship between pathophysiology of Alzheimer's disease and arteriosclerosis.
Others
Arteriosclerosis-related tests (Flow Mediated Dilation:FMD, Arterial Pressure volume Index:API, Arterial Velocity pulse Index:AVI), cerebrospinal fluid tests, Touch Panel-type Dementia Assessment Scale(TDAS)
Blood tests (total cholesterol, LDL cholesterol, HDL cholesterol, triglyceride, glucose)
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Prevention
Other |
Arteriosclerosis-related tests, cerebrospinal fluid tests, examination of cognitive function, blood tests
50 | years-old | <= |
Not applicable |
Male and Female
1) Subjects who are 20-89 years old at the time of registration
2) Alzheimer's disease patients who fulfill of the DSM-5 and NINCDS-ADRDA criteria, or mild cognitive impairment patients who fulfill of the Petersen criteria, or subjects who don't have cognitive impairment.
3) In the Alzheimer's disease and mild cognitive impairment patients, the consent from proxies is necessary.
4) Patients who performed the cerebrospinal fluid and blood tests (total cholesterol, LDL cholesterol, HDL cholesterol, triglyceride, glucose) within three months.
1) Patients who are judged difficulty depiction of brachial artery or pressure of forearm.
2) Patients who have more than 200 mmHg in resting systolic pressure.
3) Patients who are assessed by the principal investigator due to other reasons.
90
1st name | |
Middle name | |
Last name | Katsuya Urakami |
School of Health Science, Faculty of Medicine, Tottori University
Department of Biological Regulation
86 Nishicho, Yonago, Tottori, Japan
0859-38-6354
kurakami@med.tottori-u.ac.jp
1st name | |
Middle name | |
Last name | Minoru Kouzuki |
School of Health Science, Faculty of Medicine, Tottori University
Department of Biological Regulation
86 Nishicho, Yonago, Tottori, Japan
0859-38-6358
kouzuki@med.tottori-u.ac.jp
Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University
None
Self funding
NO
2016 | Year | 04 | Month | 07 | Day |
Unpublished
Completed
2016 | Year | 04 | Month | 06 | Day |
2016 | Year | 04 | Month | 11 | Day |
2016 | Year | 04 | Month | 06 | Day |
2018 | Year | 04 | Month | 09 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000025134
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