Unique ID issued by UMIN | UMIN000021406 |
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Receipt number | R000024690 |
Scientific Title | Effects of food intake and 4-week multiple curcumin ingestion on pharmacokinetics (bioavailability) of a curcumin supplement |
Date of disclosure of the study information | 2016/11/01 |
Last modified on | 2016/09/21 15:04:31 |
Effects of food intake and 4-week multiple curcumin ingestion on pharmacokinetics (bioavailability) of a curcumin supplement
Pharmacokinetics (bioavailability)
of of a curcumin supplement
Effects of food intake and 4-week multiple curcumin ingestion on pharmacokinetics (bioavailability) of a curcumin supplement
Pharmacokinetics (bioavailability)
of of a curcumin supplement
Japan |
Healthy subjects
Not applicable | Adult |
Others
NO
Effects of food intake of 4-week multiple ingestion of curcumin on bioavailability of a curcumin supplement
Bio-availability
Confirmatory
Others
Pharmacokinetics parameters
(AUC, Cmax, baseline plasma curcumin concetration)
MDA, 8-OHdG, metabolome
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Prevention
Food |
Curcumin supplement
Single oral dose of the supplement containing 30 mg of curcumin, twice a day for 4 weeks
20 | years-old | <= |
45 | years-old | >= |
Male and Female
- Subjects signed on informed consent documents
- Healthy male and female Japanese subjects at the age between 20 and 45
- Non-smoker
- Body weight <= 80 kg
- 20<=BMI<25
- Subjects whoeat 3 meals a day regulary
- Severe disease history
- Currently under treatment
- Food or drug allergy
- Regular use of curcumin-containing supplements
- Pregnant or planned on becoming pregnant
- Other unappropriate conditions judged by PI
9
1st name | |
Middle name | |
Last name | Naoki Miura |
Miura Clinic
Director
9F Higashitemma Bld., 1-7-17, Higashitemma, Kita-ku, Oosaka-shi, Osaka, 530-0044
06-6135-5200
miura@miura-cl.jp
1st name | |
Middle name | |
Last name | Makoto Terashima |
Oneness Support Co., Ltd.
Director
8F Higashitemma Bld., 1-7-17, Higashitemma, Kita-ku, Oosaka-shi, Osaka
06-4801-8917
mterashima@oneness-sup.co.jp
Kobe University Hospital
Center for Clinical Research
Health Evaluation Research Office
Association for Health Economics Research and Social Insurance and Welfare
Non profit foundation
NO
2016 | Year | 11 | Month | 01 | Day |
Unpublished
Completed
2016 | Year | 02 | Month | 26 | Day |
2016 | Year | 03 | Month | 23 | Day |
2016 | Year | 07 | Month | 31 | Day |
2016 | Year | 08 | Month | 15 | Day |
2016 | Year | 08 | Month | 20 | Day |
2016 | Year | 08 | Month | 31 | Day |
2016 | Year | 03 | Month | 09 | Day |
2016 | Year | 09 | Month | 21 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000024690
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