UMIN-CTR Clinical Trial

Basic information
Official scientific title of the study	Acute Effect of resistance exercise on cerebral blood flow
Title of the study (Brief title)	Effect of resistance exercise on cerebral blood flow
Region	Japan

Condition
Condition	healthy adults
Classification by specialty	Adult
Classification by malignancy	Others
Genomic information	NO

Objectives
Narrative objectives1	To investigate response of cerebral blood flow
Basic objectives2	Safety
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase

Assessment
Primary outcomes	cerebral blood flow in rest, immediately after exercise, 10 min after exercise.
Key secondary outcomes

In outcomes field, the entry of just a few words such as "safety" or "efficiency" will not be accepted. Specify the name of outcome measures, including the time when you plan to measure. Usually, only one primary outcome is accepted. Write the other outcomes in "secondary outcomes" field.

Base
Study type	Interventional

Study design
Basic design	Cross-over
Randomization	Non-randomized
Randomization unit
Blinding	Open -no one is blinded
Control	Dose comparison
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment

Intervention
No. of arms	3
Purpose of intervention	Prevention
Type of intervention	Other
Interventions/Control_1	1)aerobic exercise cycle exercise for 30 min the intensity is 60%HRR 2)a week for wash out 3)High-intensity resistance exercise High-intensity resistance exercise for 30 min the intensity is 80%1RM squat, bench press, bent over row, arm curl, shoulder press 10 repetition 3-4 sets 4)a week for wash out 5)Low-intensity resistance exercise High-intensity resistance exercise for 30 min the intensity is 50%1RM squat, bench press, bent over row, arm curl, shoulder press 10 repetition 3-4 sets
Interventions/Control_2	1)High-intensity resistance exercise High-intensity resistance exercise for 30 min the intensity is 80%1RM squat, bench press, bent over row, arm curl, shoulder press 10 repetition 3-4 sets 2)a week for wash out 3)Low-intensity resistance exercise High-intensity resistance exercise for 30 min the intensity is 50%1RM squat, bench press, bent over row, arm curl, shoulder press 10 repetition 3-4 sets 4)a week for wash out 5)aerobic exercise cycle exercise for 30 min the intensity is 60%HRR
Interventions/Control_3	1)Low-intensity resistance exercise High-intensity resistance exercise for 30 min the intensity is 50%1RM squat, bench press, bent over row, arm curl, shoulder press 10 repetition 3-4 sets 2)a week for wash out 3)aerobic exercise cycle exercise for 30 min the intensity is 60%HRR 4)a week for wash out 5)High-intensity resistance exercise High-intensity resistance exercise for 30 min the intensity is 80%1RM squat, bench press, bent over row, arm curl, shoulder press 10 repetition 3-4 sets
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10

In interventions field, include the details of interventions, such as duration, amount, and frequency. If the intervention includes prescription or use of medical devices, duration is required.

Eligibility
Age-lower limit	20 years-old <=
Age-upper limit	26 years-old >=
Gender	Male
Key inclusion criteria	Healthy individual
Key exclusion criteria	Circulatory system diseases
Target sample size	10

Research contact person
Name of lead principal investigator	Muraoka Isao
Organization	Waseda University
Division name	Faculty of Sport Sciences
Address	Mikajima 2-579-15, Tokorozawa
TEL	04-2947-7128
Email	nobu0902@toki.waseda.jp

Public contact
Name of contact person	Nakamura Nobuhiro
Organization	Waseda University
Division name	Graduate School of Sport Sciences
Address	Mikajima 2-579-15, Tokorozawa
TEL	04-2947-7128
Homepage URL
Email	nobu0902@toki.waseda.jp

Sponsor
Institute	Waseda University
Institute
Department

Sponsor means an organization that is responsible for plan, deployment and report of the research including funding management. It doesn't mean funding agency". Therefore, all clinical trial should have the one.

Funding Source
Organization	N/A
Organization
Division
Category of Funding Organization	Other
Nationality of Funding Organization

Other related organizations
Co-sponsor
Name of secondary funｄer(s)

Secondary IDs
Secondary IDs	NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW

Institutions
Institutions

Other administrative information
Date of disclosure of the study information	2016 Year 03 Month 01 Day

Progress
Recruitment status	Completed
Date of protocol fixation	2015 Year 08 Month 01 Day
Anticipated trial start date	2015 Year 08 Month 21 Day
Last follow-up date
Date of closure to data entry
Date trial data considered complete
Date analysis concluded

Related information
URL releasing protocol
Publication of results	Unpublished
URL releasing results
Results
Other related information

Management information
Registered date	2016 Year 02 Month 29 Day
Last modified on	2016 Year 04 Month 06 Day

Link to view the page
URL(English)	https://upload.umin.ac.jp/cgi-bin/ctr_e/ctr_view.cgi?recptno=R000024517