Unique ID issued by UMIN | UMIN000019534 |
---|---|
Receipt number | R000022591 |
Scientific Title | To reveal a way to optimize the absorption of lycopene 1.The comparing taking tomato juice with raw tomato 2.The most appropriate timing |
Date of disclosure of the study information | 2015/10/30 |
Last modified on | 2018/09/20 16:19:48 |
To reveal a way to optimize the absorption of lycopene
1.The comparing taking tomato juice with raw tomato
2.The most appropriate timing
To reveal a way to optimize the absorption of lycopene
To reveal a way to optimize the absorption of lycopene
1.The comparing taking tomato juice with raw tomato
2.The most appropriate timing
To reveal a way to optimize the absorption of lycopene
Japan |
Healthy adults
Not applicable | Adult |
Others
NO
The aims of this study are the following:
1.To reveal lycopene is absorbed more efficiently form tomato juice than raw tomato
2.To reveal the most appropriate timing for lycopene intake
Bio-availability
Lycopene concentration in chylomicron before and 2,4,6,12 h after taking the intervention food.
(measured value, amount of the change, the area under the curve)
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Prevention
Food |
<Period 1>
Food: Tomato juice
Injection period: Single
Dose: 160 mL (Lycopene 16 mg)/ 1 can
Time: Evening
Wash-out period: 1 week (between period 1 and period 2)
<Period 2>
Food: Tomato juice
Injection period: Single
Dose: 160 mL (Lycopene 16 mg)/ 1 can
Time: Afternoon
Wash-out period: 1 week (between period 2 and period 3)
<Period 3>
Food: Tomato juice
Injection period: Single
Dose: 160 mL (Lycopene 16 mg)/ 1 can
Time: Morning
Wash-out period: 1 week (between period 3 and period 4)
<Period 4>
Food: Raw tomato
Injection period: Single
Dose: About 320 g (Lycopene 16 mg)
Time: Morning
20 | years-old | <= |
50 | years-old | >= |
Male and Female
People who satisfy the following conditions will be required.
1) Who do not fit key exclusion criteria
2) Who are judged suitable for this study by principal investigator and commissioned researchers.
People who satisfy any of the following conditions will be excluded.
1) Who show hypercholesterolemia or hypertriglyceridemia
2) Who show something wrong in the liver function
3) Who have a marked surgical history of digestive system or have some problems in the respiratory system or the heart
4) Who show low absorption of lycopene
(i.e. who show lower amount of lycopene change in the serum than 0.025 microM at 6h after taking tomato juice
5) Who do not have a habit of taking three meals in a day
6) Who are pregnant or breastfeeding, or desires to get pregnant during the study period
7) Who have a tomato allergy
8) Who have a smoking habit
9) Who join other studies
10) Who do not obey the study rule
11) Who are judged unsuitable for this study by principal investigator
24
1st name | |
Middle name | |
Last name | Satoshi Sunabori |
Kagome CO.,LTD.
Innovation Division
17 Nishitomiyama, Nasushiobarashi, Tochigi, 329-2762, Japan
0287-36-2935
Satoshi_Sunabori@kagome.co.jp
1st name | |
Middle name | |
Last name | Yudai Aoki |
Kagome CO.,LTD.
Innovation Division
17 Nishitomiyama, Nasushiobarashi, Tochigi, 329-2762, Japan
0287-36-2935
Yudai_Aoki@kagome.co.jp
Kagome CO.,LTD.
None
Self funding
CPCC Co., Ltd.
Tiyoda paramedic clinic
LSI Medience Corporation
NO
2015 | Year | 10 | Month | 30 | Day |
Published
Completed
2015 | Year | 10 | Month | 16 | Day |
2015 | Year | 10 | Month | 31 | Day |
2015 | Year | 10 | Month | 28 | Day |
2018 | Year | 09 | Month | 20 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000022591
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |