Unique ID issued by UMIN | UMIN000019350 |
---|---|
Receipt number | R000022366 |
Scientific Title | Association of the pathophysiology of chronic cough refractory to specific treatments with levels of hydrogen sulfide(H2S) in serum and sputum supernatant |
Date of disclosure of the study information | 2015/10/14 |
Last modified on | 2020/07/09 00:57:05 |
Association of the pathophysiology of chronic cough refractory to specific treatments with levels of hydrogen sulfide(H2S) in serum and sputum supernatant
Association of the pathophysiology of chronic cough refractory to specific treatments with levels of hydrogen sulfide(H2S) in serum and sputum supernatant
Association of the pathophysiology of chronic cough refractory to specific treatments with levels of hydrogen sulfide(H2S) in serum and sputum supernatant
Association of the pathophysiology of chronic cough refractory to specific treatments with levels of hydrogen sulfide(H2S) in serum and sputum supernatant
Japan |
chronic cough
Pneumology |
Others
NO
To measure the concentration of hydrogen sulfide in serum and sputum supernatant in asthmatics and non-asthmatics refractory to specific treatments
Others
To measure the concentration of hydrogen sulfide in serum and sputum supernatant in asthmatics and non-asthmatics refractory to specific treatments
Elevated levels of H2S would associate with the pathophysiology of chronic cough refractory to specific treatments
Observational
16 | years-old | <= |
99 | years-old | >= |
Male and Female
Group(a) Patients with asthmatic cough lasting for 8 weeks or more despite receving adequate therapies
Group(b) Patients with asthmatic cough whose cough is well-controlled
Group(c) Patients with non-asthmatic cough lasting for 8 weeks or more despite receving specific therapies
Group(d) Controll subjects
If patients meet the following criteria, they are excluded.
Patients who
have other respiratory disease such as tuberculosis and lung cancer
currently smoke, had smoking history with 10 pack-years or more, or had quitted smoking within 6 months prior to the enrollment
120
1st name | Yoshihiro |
Middle name | |
Last name | Kanemitsu |
Nagoya City University
Dept of Respiratory Medicine, Allergy and Clinical Immunology
4678601
1 kawasumi, mizuho-cho, mizuho-ku, Nagoya, Aichi, Japan
052-853-8216
kaney32@med.nagoya-cu.ac.jp
1st name | Kensuke |
Middle name | |
Last name | Fukumitsu |
Nagoya City University
Dept of Respiratory Medicine, Allergy and Clinical Immunology
4678601
1 kawasumi, mizuho-cho, mizuho-ku, Nagoya, Aichi, Japan
052-853-8216
k-fkmt@med.nagoya-cu.ac.jp
Nagoya City University Dept of Respiratory Medicine, Allergy and Clinical Immunology
Nagoya City University Dept of Respiratory Medicine, Allergy and Clinical Immunology
Self funding
Nagoya City University
1 kawasumi, mizuho-cho, mizuho-ku, Nagoya, Aichi, Japan
052-858-7215
clinical_research@med.nagoya-cu.ac.jp
NO
2015 | Year | 10 | Month | 14 | Day |
Unpublished
113
Delay expected |
Serum or sputum supernatant hydrogen sulfide were similar between patients with persistent cough and those without cough. We are plannnig a new research plan using optout for patients who have already measured serum or sputum supernatant hydrogen sulfide.
Completed
2015 | Year | 09 | Month | 29 | Day |
2015 | Year | 09 | Month | 29 | Day |
2015 | Year | 10 | Month | 21 | Day |
2018 | Year | 09 | Month | 29 | Day |
2018 | Year | 09 | Month | 29 | Day |
2018 | Year | 09 | Month | 29 | Day |
2020 | Year | 03 | Month | 31 | Day |
Design
cross-sectional study
Enrollment
patients who met the criteria of this study will be enrolled between Oct 2015 and Sep 2018
Measurement items
levels of H2S in serum and sputum supernatant
2015 | Year | 10 | Month | 14 | Day |
2020 | Year | 07 | Month | 09 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000022366