Unique ID issued by UMIN | UMIN000019325 |
---|---|
Receipt number | R000022345 |
Scientific Title | Enzalutamide treatment sensitivity recovery effect of docetaxel treatment after relapse of enzalutamide treatment for castration-resistant prostate cancer patients |
Date of disclosure of the study information | 2015/11/01 |
Last modified on | 2020/10/16 10:10:36 |
Enzalutamide treatment sensitivity recovery effect of docetaxel treatment after relapse of enzalutamide treatment for castration-resistant prostate cancer patients
ESRED study
Enzalutamide treatment sensitivity recovery effect of docetaxel treatment after relapse of enzalutamide treatment for castration-resistant prostate cancer patients
ESRED study
Japan |
Castration-resistant prostate cancer
Urology |
Malignancy
NO
Exploring enzalutamide treatment sensitivity recovery effect of docetaxel treatment after relapse of enzalutamide treatment for castration-resistant prostate cancer patients
Efficacy
Exploratory
Pragmatic
Not applicable
Biochemical-free survival rate (Prostate specific antigen progression free survival rate (PSA-PFS)) after enzalutamide retreatment
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Enzaltamide 160mg per day by oral after docetaxel (at a dose of 70 mg/m2 every three or four weeks for six cycles)
20 | years-old | <= |
Not applicable |
Male
1. 20 years old or more
2. Diagnosed as prostate cancer by histological examination
3. Testosterone < 50ng/dL
4. Progression on the image or PSA relapse
5. 2 months or more has passed from operation for metastasis or radiation therapy.
6. PS of ECOG; 0-2
7. Liver and renal function are adequate
8. Life expectancy is more than 6 months
1. Patients treated by chemotherapy
2. Patients judged to be inappropriate to perform this study by investigator
20
1st name | |
Middle name | |
Last name | Tsutomu Nishiyama |
Uonuma Institute of Community Medicine
Niigata University Medical and Dental Hospital
Department of Urology
Urasa 4132, Minamiuonumashi, Niigata 949-7302, Japan
025-777-3200
nisiyama@med.niigata-u.ac.jp
1st name | |
Middle name | |
Last name | Tsutomu Nishiyama |
Uonuma Institute of Community Medicine Niigata University Medical and Dental Hospital
Department of Urology
Urasa 4132, Minamiuonumashi, Niigata 949-7302, Japan
025-777-3200
nisiyama@med.niigata-u.ac.jp
Department of Urology
Uonuma Institute of Community Medicine
Niigata University Medical and Dental Hospital
Department of Urology
Uonuma Institute of Community Medicine
Niigata University Medical and Dental Hospital
Self funding
NO
2015 | Year | 11 | Month | 01 | Day |
Unpublished
Terminated
2015 | Year | 10 | Month | 07 | Day |
2018 | Year | 03 | Month | 31 | Day |
2015 | Year | 11 | Month | 30 | Day |
2018 | Year | 03 | Month | 31 | Day |
2015 | Year | 10 | Month | 13 | Day |
2020 | Year | 10 | Month | 16 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000022345