Unique ID issued by UMIN | UMIN000020090 |
---|---|
Receipt number | R000022234 |
Scientific Title | The Effect of Kiwifruit on Constipation with or without Irritable Bowel Syndrome |
Date of disclosure of the study information | 2016/01/01 |
Last modified on | 2024/09/16 23:15:06 |
The Effect of Kiwifruit on Constipation with or without Irritable Bowel Syndrome
Kiwifruit on Constipation
The Effect of Kiwifruit on Constipation with or without Irritable Bowel Syndrome
Kiwifruit on Constipation
Japan | Australia | Europe |
irritable bowel syndrome with constipation (IBS-C)
functional constipation (FC)
Medicine in general | Gastroenterology | Psychosomatic Internal Medicine |
Others
NO
To test the hypothesis that taking kiwifruit improves symptoms in IBS-C and FC.
Efficacy
Confirmatory
Explanatory
Phase III
complete spontaneous bowel movement (CSBM)
4 weeks
spontaneous bowel movement (SBM)
GI symptoms
GI motility
blood examination
gut microbiota
Interventional
Cross-over
Randomized
Individual
Double blind -all involved are blinded
Active
NO
NO
Institution is considered as a block.
YES
Central registration
2
Treatment
Food |
kiwifruit 2 per day for 4 weeks-(wash out period)-psyllium 7.5 g per day for 4 weeks
psyllium 7.5 g per day for 4 weeks-(wash out period)-kiwifruit 2 per day for 4 weeks
18 | years-old | <= |
65 | years-old | >= |
Male and Female
Rome III criteria
Potential participants will be excluded if they have any alarm features associated with bowel habit (recent changes in bowel habit (<3 months), rectal bleeding, weight loss, occult blood in stools, anaemia), anal fissures, bleeding haemorrhoids, and family history of GI cancer or IBD.
Chronic disease (cardiovascular, cancer, renal failure, previous gastrointestinal surgery (not including appendectomy or cholecystectomy), neurological conditions (e.g. multiple sclerosis, spinal chord injury, stroke.
60
1st name | |
Middle name | |
Last name | Shin Fukudo |
Tohoku University Graduate School of Medicine
Department of Behavioral Medicine
2-1 Seiryo, Aoba, Sendai 980-8575 Japan
022-717-8214
sfukudo@med.tohoku.ac.jp
1st name | |
Middle name | |
Last name | Yohei Ohkawa |
Tohoku University Graduate School of Medicine
Department of Behavioral Medicine
2-1 Seiryo, Aoba, Sendai 980-8575 Japan
022-717-8160
pesopesogin1325@yahoo.co.jp
Tohoku University Graduate School of Medicine
Zespri International Ltd, NZ
Profit organization
New Zealand
University of Otago
University of Bologna
NO
Tohoku University Graduate School of Medicine
2016 | Year | 01 | Month | 01 | Day |
Unpublished
Completed
2015 | Year | 12 | Month | 31 | Day |
2015 | Year | 12 | Month | 21 | Day |
2016 | Year | 09 | Month | 26 | Day |
2017 | Year | 06 | Month | 20 | Day |
2017 | Year | 10 | Month | 31 | Day |
2017 | Year | 12 | Month | 15 | Day |
2018 | Year | 02 | Month | 28 | Day |
2015 | Year | 12 | Month | 06 | Day |
2024 | Year | 09 | Month | 16 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000022234