Unique ID issued by UMIN | UMIN000018599 |
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Receipt number | R000021526 |
Scientific Title | Effect of ezetimibe on PCSK9 concentrations in patients with type 2 diabetes and dyslipidemia |
Date of disclosure of the study information | 2015/08/08 |
Last modified on | 2016/03/08 11:53:39 |
Effect of ezetimibe on PCSK9 concentrations in patients with type 2 diabetes and dyslipidemia
Effect of ezetimibe on PCSK9 concentrations in patients with type 2 diabetes and dyslipidemia
Effect of ezetimibe on PCSK9 concentrations in patients with type 2 diabetes and dyslipidemia
Effect of ezetimibe on PCSK9 concentrations in patients with type 2 diabetes and dyslipidemia
Japan |
Hypercholesterolemia
Medicine in general |
Others
NO
This study evaluated the effect of ezetimibe monotherapy or in combination with a statin on serum levels of PCSK9 in patients with type 2 diabetes and hypercholesterolemia.
Pharmacokinetics
Change in PCSK9 concentration after ezetimibe treatment
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
ezetimibe, 10mg/day after breakfast,for 6 months
20 | years-old | <= |
Not applicable |
Male and Female
type 2 diabetes mellitus and hypercholesterolemia
1)TG>400mg/dl
2)use of insulin
3)pregnant
4)allergy agignst treatment drug
5)severe liver disease
6)severe kideny disease
7)history of myocardial infarction or unstable angina within 3 months
8)secondary hyperlimidemia, drug-induced hyperlimidemia, familial hypercholeaterolemia
9)use of ezetimib or fibrate
10)subject who is not suitable for this study
20
1st name | |
Middle name | |
Last name | Toru Miyoshi |
Okayama University Hospital
Cardiovascular Medicine
2-5-1, Shikata-cho, Kita-ku, Okayama
086-235-7351
miyoshit@cc.okayama-u.ac.jp
1st name | |
Middle name | |
Last name | Toru Miyoshi |
Okayama University Hospital
Cardiovascular Medicine
2-5-1, Shikata-cho, Kita-ku, Okayama
086-235-7351
miyoshit@cc.okayama-u.ac.jp
Okayama University Hospital, Depertment of Cardiovascular Medicine
Okayama University Hospital, Depertment of Cardiovascular Medicine
Other
NO
2015 | Year | 08 | Month | 08 | Day |
Published
Completed
2015 | Year | 03 | Month | 01 | Day |
2015 | Year | 03 | Month | 01 | Day |
2015 | Year | 10 | Month | 01 | Day |
2015 | Year | 08 | Month | 08 | Day |
2016 | Year | 03 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000021526
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