Unique ID issued by UMIN | UMIN000018563 |
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Receipt number | R000021481 |
Scientific Title | A study of the efficacy of preoperative chemotherapy and radiation therapy for rectal cancer |
Date of disclosure of the study information | 2015/08/06 |
Last modified on | 2019/03/01 12:51:06 |
A study of the efficacy of preoperative chemotherapy and radiation therapy for rectal cancer
A study of the efficacy of preoperative chemotherapy and radiation therapy for rectal cancer
A study of the efficacy of preoperative chemotherapy and radiation therapy for rectal cancer
A study of the efficacy of preoperative chemotherapy and radiation therapy for rectal cancer
Japan |
rectal cancer
Gastrointestinal surgery |
Malignancy
NO
To evaluate the efficacy of preoperative chemoradiotherapy for rectal cancer in retrospective study.
Efficacy
3-year local control rate
(1)3-year over-all survival rate
(2)Complete chemoradiotherapy rate
(3)Postoperative complications rate
Observational
Not applicable |
Not applicable |
Male and Female
(1)Diagnosis of rectal cancer in preoperative pathology (tissue type does not matter).
(2) Case of rectal cancer after CRT in a preoperative diagnosis of A ,AI or Dukes C are diagnosed (Japanese Classification of Colorectal Carcinoma the 7th edition) and the cases that made the CRT.
(3) presence or absence of distant metastases does not matter
(4) presence or absence of primary tumor resection does not matter
(1)Preoperative diagnosis of rectal cancer in M or MP and N0 Stage I (Japanese Classification of Colorectal Carcinoma the 7th edition)
(2)Patients who principal investigator has determined to be inappropriate as a subject
40
1st name | |
Middle name | |
Last name | Masakazu Yamamoto |
Tokyo Women's Medical University
Department of Surgery, Institute of Gastroenterology
8-1 Kawada-cho, Shinjuku-ku, Tokyo, Japan
+81-3-3353-8111
yamamoto.ige@twmu.ac.jp
1st name | |
Middle name | |
Last name | Ryosuke Nakagawa |
Tokyo Women's Medical University
Department of Surgery, Institute of Gastroenterology
8-1 Kawada-cho, Shinjuku-ku, Tokyo, Japan
+81-3-3353-8111
nakagawa.ryosuke@twmu.ac.jp
Tokyo Women's Medical University Hospital
None
Other
NO
2015 | Year | 08 | Month | 06 | Day |
Published
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452334/
The completion rate of CRT was high at 94% (n?=?29/31). The downstaging rate of CRT was 61% (n?=?19/31). The pathological complete response rate was 6.5% (n?=?2/31). Significant differences were observed in the 3-year local recurrence rate between the two groups (P?<?0.05).
Completed
2014 | Year | 12 | Month | 25 | Day |
2014 | Year | 12 | Month | 25 | Day |
We evaluate the efficacy of preoperative chemo-radiation therapy for the lower rectal cancer in our department between 2009 and 2013. We examine treatment results (patient factors, pathology factors, surgery factors, prognosis)
This study is a retrospective cohort study to evaluate the rate of 3 years local control.
2015 | Year | 08 | Month | 06 | Day |
2019 | Year | 03 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000021481
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