Unique ID issued by UMIN | UMIN000018513 |
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Receipt number | R000021427 |
Scientific Title | Major Increases in Morning Glucose Levels May Predict Nocturnal Hypoglycemia in Type 2 Diabetes -retrospective study- |
Date of disclosure of the study information | 2015/07/31 |
Last modified on | 2015/07/31 22:17:41 |
Major Increases in Morning Glucose Levels May Predict Nocturnal Hypoglycemia in Type 2 Diabetes -retrospective study-
Increases glucose predict hypoglycemia.
Major Increases in Morning Glucose Levels May Predict Nocturnal Hypoglycemia in Type 2 Diabetes -retrospective study-
Increases glucose predict hypoglycemia.
Japan |
type 2 diabetes
Endocrinology and Metabolism |
Others
NO
Nocturnal hypoglycemia may be associated with increased morning glucose levels; however, the mechanism of this relationship remains unknown.
Safety
Pre-breakfast glucose level, highest postprandial glucose level within 3 h after breakfast, time from start of breakfast to the highest postprandial glucose level, difference between pre-breakfast and highest postprandial breakfast glucose levels, area under the curve (AUC) (180 mg/dL) for glycemic variability within 3 h after breakfast, post-breakfast glucose gradient, and the increased glucose level/pre-breakfast glucose level ratio were calculated. We analyzed the associations between these factors and nocturnal hypoglycemia (<70 mg/dL from 0:00 to 8:00) using logistic regression analysis. ROC analysis was used to determine optimal cut-off values to predict nocturnal hypoglycemia.
Observational
20 | years-old | <= |
90 | years-old | > |
Male and Female
type 2 diabetes who underwent continuous glucose monitoring (CGM) during admission.
take glucose
take alpha-GI
106
1st name | |
Middle name | |
Last name | Soichi Takeishi |
Ichinomiyanishi Hospital
Department of Endocrinology and Diabetes
1, Kaimei-hira, Ichinomiya-city, Aichi, 494-0001
0586-48-0077
souichi19811225@yahoo.co.jp
1st name | |
Middle name | |
Last name | Soichi Takeishi |
Ichinomiyanishi Hospital
Department of Endocrinology and Diabetes
1, Kaimei-hira, Ichinomiya-city, Aichi, 494-0001
0586-48-0077
souichi19811225@yahoo.co.jp
Ichinomiyanishi Hospital
Ichinomiyanishi Hospital
Self funding
NO
2015 | Year | 07 | Month | 31 | Day |
Unpublished
Completed
2015 | Year | 06 | Month | 11 | Day |
2015 | Year | 06 | Month | 11 | Day |
We retrospectively analyzed 106 patients with type 2 diabetes who underwent continuous glucose monitoring (CGM) during admission. Pre-breakfast glucose level, highest postprandial glucose level within 3 h after breakfast, time from start of breakfast to the highest postprandial glucose level, difference between pre-breakfast and highest postprandial breakfast glucose levels, area under the curve (AUC) (180 mg/dL) for glycemic variability within 3 h after breakfast, post-breakfast glucose gradient, and the increased glucose level/pre-breakfast glucose level ratio were calculated. We analyzed the associations between these factors and nocturnal hypoglycemia (<70 mg/dL from 0:00 to 8:00) using logistic regression analysis. ROC analysis was used to determine optimal cut-off values to predict nocturnal hypoglycemia.
2015 | Year | 07 | Month | 31 | Day |
2015 | Year | 07 | Month | 31 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000021427
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