Unique ID issued by UMIN | UMIN000018474 |
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Receipt number | R000021342 |
Scientific Title | Cardiovascular prognostic coupling study in Japan |
Date of disclosure of the study information | 2015/07/29 |
Last modified on | 2019/08/01 10:05:39 |
Cardiovascular prognostic coupling study in Japan
Cardiovascular prognostic coupling study in Japan(Coupling Registry)
Cardiovascular prognostic coupling study in Japan
Cardiovascular prognostic coupling study in Japan(Coupling Registry)
Japan |
Cardiovascular disease
Cardiology |
Others
NO
This study aimed to clarify the relationship between the blood pressure variability and vascular properties in hypertensive, and to investigate its relationships with the onset of cardiovascular events in patients at high risk of cardiovascular disease.
Efficacy
Time to major cardiovascular events*.
*Major cardiovascular events; a composite of cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage, unknown type of stroke,
myocardial infarction, cardiovascular intervention due to angina pectoris, and sudden death.
1. Time to various events onset*.
* In addition to each component of major cardiovascular events, followings are considered as "various events": hospitalization by angina pectoris; hospitalization by heart failure, aortic dissection; occlusive arteriosclerosis; end stage renal insufficiency; doubling of serum creatinine values; new onset of atrial fibrillation; dementia; need of nursing care; total death.
2. Change in blood pressure
3. Increase of CAVI or ABI value.
4. Development of left ventricular hypertrophy
5. Adverse event
Observational
30 | years-old | <= |
Not applicable |
Male and Female
Patient with at least one of the following cardiovascular risk factor:
1. Diabetes, glucose tolerance disorder
2. Dyslipidemia
3. high-normal normotension and grade I - III hypertension (>130/85 mmHg)
4. Current smoking
5. Renal disease (eGFR <= 60 or positive proteinuria)
6. Past history of cardiovascular disease (coronary artery disease, cerebrovascular disorder or non-cardiogenic cerebrovascular disorder, aortic dissection, peripheral artery disease, history of hospitalization by heart failure)
7. atrial fibrillation
8. Metabolic syndrome
9. Chronic obstructive pulmonary disease
10. Sleep apnea syndrome
1. Patients with chronic renal failure in haemodialysis
2. Other seriously ill patients (e.g. end stage of cancer, active connective tissue disease)
3. Alcohol addiction
4. Drug addiction
5. Patients who cannot visit a hospital alone by walk
6. Patients who cannot give informed consent by themselves
7. Patients who are judged to be inappropriate for the study by physician
7000
1st name | Kazuomi |
Middle name | |
Last name | Kario |
Jichi Medical University School of
Medicine
Division of Cardiovascular Medicine, Department of Medicine
329-0498
3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498,Japan.
0285-58-7344
kkario@jichi.ac.jp
1st name | Kazuomi |
Middle name | |
Last name | Kario |
Jichi Medical University School of
Division of Cardiovascular Medicine, Department of Medicine
329-0498
3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498,Japan.
0285-58-7344
coupling@jichi.ac.jp
Jichi Medical University School of
Medicine
Community Medicine Cardiovascular
Research Asia IT Network Center,
Division of Cardiovascular Medicine
Jichi Medical University School of
Medicine
Self funding
Japan
FUKUDA DENSHI CO.,LTD.
Jichi Medical School clinical study support center
3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan.
0285-58-8933
rinri@jichi.ac.jp
NO
鷲谷病院(栃木県)、フクダ電子株式会社(東京都)、今別町国民健康保険今別診療所(青森県)、
沖縄県立中部病院(沖縄県)、遠賀中間医師会おんが病院(福岡県)、かわしま循環器内科(栃木県)、
久保田クリニック(東京都)、小竹町立病院(福岡県)、東吾妻町国民健康保険診療所(群馬県)、
藤田脳神経外科医院(香川県)、南三陸病院(宮城県)、山際クリニック(愛知県)、
周防大島町立東和病院(山口県)、岩国市医療センター医師会病院(山口県)、
まつい内科クリニック(山口県)、石橋内科医院(茨城県)、阿部内科医院(兵庫県)、
佐久総合病院佐久医療センター(長野県)、南和歌山医療センター(和歌山県)、表参道内科眼科(東京都)、
JCHOうつのみや病院(栃木県)、富士通クリニック(神奈川県)、
馬渡島診療所(佐賀県)、八代市椎原診療所(熊本県)、国民健康保険大間病院(青森県)、
大島診療所(福岡県)、国際医療福祉大学病院(栃木県)、結城病院(茨城県)、新小山市民病院(栃木県)、
とちぎメディカルセンターしもつが(栃木県)
2015 | Year | 07 | Month | 29 | Day |
Unpublished
6068
No longer recruiting
2015 | Year | 03 | Month | 26 | Day |
2015 | Year | 03 | Month | 26 | Day |
2015 | Year | 07 | Month | 29 | Day |
2027 | Year | 10 | Month | 31 | Day |
2028 | Year | 01 | Month | 31 | Day |
2028 | Year | 03 | Month | 31 | Day |
2029 | Year | 03 | Month | 31 | Day |
This is a prospective cohort study.
Follow up period: Seven years.
Patients are followed up regularly for seven years every one year from a registration day.
2015 | Year | 07 | Month | 29 | Day |
2019 | Year | 08 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000021342
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