Unique ID issued by UMIN | UMIN000021228 |
---|---|
Receipt number | R000021270 |
Scientific Title | The association between coronary plaque characteristics and glucose fluctuation assesed by coronary imaging devices and continuous glucose monitoring |
Date of disclosure of the study information | 2016/02/27 |
Last modified on | 2022/03/15 18:55:46 |
The association between coronary plaque characteristics and glucose fluctuation assesed by coronary imaging devices and continuous glucose monitoring
The Association Between Coronary plaque characteristics and glucose fluctuation assesed by coronary imaging devices and Continuous Glucose Monitoring:ABC-CGM study
The association between coronary plaque characteristics and glucose fluctuation assesed by coronary imaging devices and continuous glucose monitoring
The Association Between Coronary plaque characteristics and glucose fluctuation assesed by coronary imaging devices and Continuous Glucose Monitoring:ABC-CGM study
Japan |
Angina pectoris with impaired glucose torerance or diabetes mellitus and patients who are suspected that disease
Cardiology | Endocrinology and Metabolism |
Others
YES
This study aims to investigate the effect of glucose fluctuation on coronary plaque properties and vessel healing after stenting, and to assess the impact of glucose fluctuation on long term outcome in patients with coronary artery disease, and to investigate the association of glucose fluctuation,inflammatory cells, immune cells assessd by flowcytometry and enterobacterial flora
Others
Pathophysiology
Not applicable
1.Coronary plaque characteristics and neointimal characteristics in stent using the optical coherence tomography (OCT) and intravascular ultrasound(IVUS) and coronary angiography at the time of treatment, nine(six to twelve)months and three(twe to four)years.
2.Circadian rhythm in the blood glucose using CGM
3.Association between atherosclerosis assessed by IVUS or OCT and subsets of monocyte and Tcell.
The following at the time of treatment, nine(six to twelve)months and three(twe to four)years
1.Glucose, IRI, CPR assesed by glucose tolerance test.
2.Intima- media thickness(IMT) assesed by carotid artery ultrasound.
3.Endothelial function assessed by FMD.
4.Monocyte and T lymphocyte assesed by flowcytometry.
5.Bacterial flora in the intestine.
6.Inflammatory cell marker associated with arteriosclerosis.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Prospective observational study
Patients with impaired glucose torelance who have a plan to receive PCI for coronary artery disease.
Patinets with diagnosed or suspected impaired glucose torelance who had a history of coronary stenting.
1)Patients with renal dysfunction(Creatinin level is more than 2.0mg/ml) or reciving hemodaialysis.
2)the patients who have had heart failure (NYHA >III)
3)patients with any malignant tumor or very ill condition
4)pregnant women or women at risk of becoming pregnant
200
1st name | Toshirou |
Middle name | |
Last name | Shinke |
Kobe univercity hospital
Cardiovascular medicine
650-0017
7-5-2 Kusunoki-cho, Chuo-ku, Kobe City,650-0017
078-382-5111
shinke@med.kobe-u.ac.jp
1st name | Hiroyuki |
Middle name | |
Last name | Yamamoto |
Kobe university hospital
Cardiovascular medicine
6500017
7-5-2 Kusunoki-cho, Chuo-ku, Kobe City,650-0017
078-382-5111
y0493589m@hotmail.co.jp
Kobe University Hospital department of cardiovascular medicne
Kobe university
Self funding
Japan
Kobe university hospital
7-5-2 Kusunoki-cho, Chuo-ku, Kobe City
078-382-5111
y0493589m@hotmail.co.jp
NO
神戸大学医学部付属病院(兵庫県)
2016 | Year | 02 | Month | 27 | Day |
Unpublished
Completed
2012 | Year | 06 | Month | 01 | Day |
2016 | Year | 08 | Month | 08 | Day |
2015 | Year | 04 | Month | 01 | Day |
2021 | Year | 03 | Month | 31 | Day |
2021 | Year | 03 | Month | 31 | Day |
Prospective observational study
1.IVUS and OCT analysis at the time of receiving PCI or stent follow up.
And carotid artery ultrasound, continuous glucose monitoring(CGM), flowcytometry, fecal examination at the time.
2.IVUS and OCT analysis,corotid artery ultrasound, CGM, flowcytometry, fecal examination at 9(from 6 to 12)months and 2(from 1 to 3)years after stent implantation.
2016 | Year | 02 | Month | 27 | Day |
2022 | Year | 03 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000021270