Unique ID issued by UMIN | UMIN000018280 |
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Receipt number | R000021159 |
Scientific Title | Clinical study of the administration method of antithrombin agent |
Date of disclosure of the study information | 2015/07/21 |
Last modified on | 2015/07/12 23:28:21 |
Clinical study of the administration method of antithrombin agent
Clinical study of the administration method of antithrombin agent
Clinical study of the administration method of antithrombin agent
Clinical study of the administration method of antithrombin agent
Japan |
sepsis indused disseminated intravascular coagulation
Intensive care medicine |
Others
NO
To determine whether continuous administration of antithrombin agent or once-daily administration of antithrombin agent is more effective for sepsis indused DIC
Efficacy
Confirmatory
Disseminated intravascular coagulation resolution rates
28-day survival rate, AT activity change
Interventional
Parallel
Randomized
Open -no one is blinded
Active
2
Treatment
Medicine |
AT agent is administered at 1500 U once per day for 3 days
AT agent is administered by continuous infusion 1500 U per day for 3 days, after 1000 U loading dose is administered
20 | years-old | <= |
Not applicable |
Male and Female
1. sepsis
2. JAAM DIC score is 4 or greater
3. AT activity is less than 70
1. other DIC agent for DIC treatment
2. use of anticoagulants, antiplatelet agents, antithrombotics, exception of heparin locks, heparin flushes or deep-vein thrombosis prophykaxis, and anticoaglants for renal replacement therapy
100
1st name | |
Middle name | |
Last name | Eiji Isotani |
Tokyo women's medical university
medical center east, Emergency and Critical Care Center
2-1-10 nishiogu, arakasa-ku, Tokyo
03-3810-1111
isotaner@dnh.twmu.ac.jp
1st name | |
Middle name | |
Last name | Hiroyuki Takahashi |
Tokyo women's medical university
medical center east, Emergency and Critical Care Center
2-1-10 nishiogu, arakasa-ku, Tokyo
03-3810-1111
htakahashi-tmd@umin.ac.jp
Tokyo women's medical university
none
Other
NO
2015 | Year | 07 | Month | 21 | Day |
Unpublished
Enrolling by invitation
2015 | Year | 07 | Month | 12 | Day |
2015 | Year | 07 | Month | 21 | Day |
2015 | Year | 07 | Month | 12 | Day |
2015 | Year | 07 | Month | 12 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000021159
Research Plan | |
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Research case data | |
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