Unique ID issued by UMIN | UMIN000017629 |
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Receipt number | R000020428 |
Scientific Title | The effect of royal jelly on prevention of postmenopausal bone loss. |
Date of disclosure of the study information | 2015/05/20 |
Last modified on | 2020/11/24 11:43:58 |
The effect of royal jelly on prevention of postmenopausal bone loss.
Royal jelly and postmenopausal bone loss
The effect of royal jelly on prevention of postmenopausal bone loss.
Royal jelly and postmenopausal bone loss
Japan |
Postmenopausal bone loss
Endocrinology and Metabolism | Obstetrics and Gynecology | Orthopedics |
Adult |
Others
NO
To investigate the effect of royal jelly on prevention of postmenopausal bone loss.
Efficacy
Bone mineral density, bone turnover markers
Interventional
Parallel
Randomized
Cluster
Double blind -all involved are blinded
Placebo
2
Prevention
Food |
Freeze dried law royal jelly 3,000mg/day (1,000mg as active ingredient) for 6 months.
Placebo
45 | years-old | <= |
60 | years-old | >= |
Female
Healthy women (without risks of fracture) within 5 years of post-menopause.
Women who are allergic to royal jelly, women with asthma, women who have complications and medications that would affect bone metabolism, and women who need osteoporosis medication.
70
1st name | Hiroshi |
Middle name | |
Last name | Matsushita |
AIchi Medical University School of Medicine
Department of Obstetrics and Gynecology
480-1195
1-1 Yazakokarimata, Nagakute, Aichi 480-1195
0561-62-3311
hirosm@aichi-med-u.ac.jp
1st name | Hiroshi |
Middle name | |
Last name | Matsushita |
Aichi Medical University School of Medicine
Department of Obstetrics and Gynecology
480-1195
1-1 Yazakokarimata, Nagakute, Aichi 480-1195
0561-62-3311
hirosm@aichi-med-u.ac.jp
Aichi Medical University School of Medicine
Japan Royal Jelly Fair Trade Council
Non profit foundation
Aichi Medical University School of Medicine
1-1 Yazakokarimata, Nagakute, Aichi 480-1195
0561-62-3311
syomu@aichi-med-u.ac.jp
NO
愛知医科大学
2015 | Year | 05 | Month | 20 | Day |
https://www.tandfonline.com/doi/full/10.1080/13697137.2020.1806815
Published
https://www.tandfonline.com/doi/full/10.1080/13697137.2020.1806815
72
1) Although women in the placebo group experienced a significant loss of BMD and deterioration in HSA parameters of the femur, no significant differences were found in these parameters in women in the RJ group.
2) The levels of P1NP and TRACP-5b decreased significantly in the placebo group; however, the total P1NP level, a marker of bone formation, was not significantly different in the RJ group at postintervention compared with baseline.
2020 | Year | 11 | Month | 24 | Day |
2020 | Year | 09 | Month | 03 | Day |
Seventy-two healthy postmenopausal women aged 45-60?years within 5?years after menopause.
Participants were randomized into two groups: women in the RJ group (n?=?36) received capsules containing dried RJ (equivalent to 3000?mg of fresh RJ); and women in the placebo group (n?=?36) received placebo daily for 6?months.
None
Bone mineral density (BMD) of the lumbar spine (L2-L4) and left proximal femur, hip structural analysis (HSA) of the left hip, and bone turnover markers were measured.
Completed
2015 | Year | 04 | Month | 24 | Day |
2015 | Year | 04 | Month | 24 | Day |
2015 | Year | 05 | Month | 20 | Day |
2016 | Year | 03 | Month | 22 | Day |
2015 | Year | 05 | Month | 20 | Day |
2020 | Year | 11 | Month | 24 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000020428
Research Plan | |
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Registered date | File name |
2020/11/24 | Royal Jelly Trial 研究計画書.pdf |
Research case data specifications | |
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Registered date | File name |
Research case data | |
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