Unique ID issued by UMIN | UMIN000017578 |
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Receipt number | R000020369 |
Scientific Title | Platinum concentration in sentinel lymph nodes after preoperative intra-arterial cisplatin chemotherapy targeting oral cancer |
Date of disclosure of the study information | 2015/05/15 |
Last modified on | 2015/05/15 08:01:22 |
Platinum concentration in sentinel lymph nodes after preoperative intra-arterial cisplatin chemotherapy targeting oral cancer
Platinum concentration in sentinel lymph nodes
Platinum concentration in sentinel lymph nodes after preoperative intra-arterial cisplatin chemotherapy targeting oral cancer
Platinum concentration in sentinel lymph nodes
Japan |
untreated oral cancer
Oto-rhino-laryngology |
Malignancy
NO
To investigate intra-arterially injected cisplatin distribution to sentinel lymph nodes
Pharmacokinetics
To compare platinum concentrations in sentinel lymph nodes and non-sentinel lymph nodes
1. Presence of metastasis to sentinel lymph nodes
2. histopathological effect to metastatic sentinel lymph nodes
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine | Maneuver |
angiography
intra-arterial infusion of cisplatin
sentinel lymph node biopsy
20 | years-old | <= |
Not applicable |
Male and Female
1. Histologically proven squamous cell carcinoma
2. Planned surgery for primary tumor
3. Written informed consent
1. Distant metastasis
2. Planned reconstruction by free flap transfer after primary tumor resection
10
1st name | |
Middle name | |
Last name | Akihiro Homma |
Hokkaido University Graduate School of Medicine
Department of Otolaryngology-Head and Neck Surgery
Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan
011-706-5958
ak-homma@med.hokudai.ac.jp
1st name | |
Middle name | |
Last name | Akihiro Homma |
Hokkaido University Graduate School of Medicine
Department of Otolaryngology-Head and Neck Surgery
Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan
011-706-5958
ak-homma@med.hokudai.ac.jp
Department of Otolaryngology-Head and Neck Surgery, Hokkaido University Graduate School of Medicine
Department of Otolaryngology-Head and Neck Surgery, Hokkaido University Graduate School of Medicine
Self funding
NO
2015 | Year | 05 | Month | 15 | Day |
Published
Completed
2009 | Year | 10 | Month | 30 | Day |
2009 | Year | 10 | Month | 30 | Day |
2015 | Year | 05 | Month | 15 | Day |
2015 | Year | 05 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000020369
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