Unique ID issued by UMIN | UMIN000017386 |
---|---|
Receipt number | R000020176 |
Scientific Title | A prospective randomized trial of potassium competitive acid blocker vs proton pump inhibitors on effect of ulcer healing after endoscopic submucosal dissection of gastric neoplasia |
Date of disclosure of the study information | 2015/05/02 |
Last modified on | 2016/06/01 09:11:51 |
A prospective randomized trial of potassium competitive acid blocker vs proton pump inhibitors on effect of ulcer healing after endoscopic submucosal dissection of gastric neoplasia
Comparison of P-CAB and PPI on effect of ulcer healing after endoscopic submucosal dissection of gastric neoplasia
A prospective randomized trial of potassium competitive acid blocker vs proton pump inhibitors on effect of ulcer healing after endoscopic submucosal dissection of gastric neoplasia
Comparison of P-CAB and PPI on effect of ulcer healing after endoscopic submucosal dissection of gastric neoplasia
Japan |
Patients with gastric neoplasia (gastric adenoma, early gastric cancer)
Gastroenterology |
Malignancy
NO
To compare the effect of vonoprazan fumarate 20mg/day and rabeprazole 10mg/day on ulcer healing after endoscopic submucosal dissection of gastric neoplasia.
Safety,Efficacy
Confirmatory
Gastric ulcer stage and ulcer size reduction rate after 4 weeks treatment
Rate of post-operative bleeding
Interventional
Parallel
Randomized
Open -no one is blinded
Active
2
Treatment
Medicine |
Vonoprazan (Takecab) 20mg orally once a day in the morning
Rabeprazole (Pariet) 10mg orally once a day in the morning
20 | years-old | <= |
Not applicable |
Male and Female
1.Patients who undergo ESD for early gastric cancer or gastric adenoma.
2.Patients who give a written informed consent.
1.Pregnancy or lactation.
2.Past history of allergy for the drugs used in this therapy.
3.Patients on some form of antithrombotic therapy or NSAIDs, adrenocorticosteroid.
4.Severe liver dysfunction, Severe renal dysfunction, Severe heart dysfunction.
5.Patients who are disqualified for the study by physicians.
40
1st name | |
Middle name | |
Last name | Hiroya Ueyama |
Juntendo University School of Medicine
Department of Gastroenterology
2-1-1 Hongo, Bunkyo-Ku, Tokyo 113-8421, Japan
03-3813-3111
psyro@juntendo.ac.jp
1st name | |
Middle name | |
Last name | Hiroya Ueyama |
Juntendo University School of Medicine
Department of Gastroenterology
2-1-1 Hongo, Bunkyo-Ku, Tokyo 113-8421, Japan
03-3813-3111
psyro@juntendo.ac.jp
Department of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan
None
Self funding
NO
2015 | Year | 05 | Month | 02 | Day |
Unpublished
Completed
2015 | Year | 05 | Month | 01 | Day |
2015 | Year | 05 | Month | 07 | Day |
2016 | Year | 05 | Month | 31 | Day |
2015 | Year | 05 | Month | 01 | Day |
2016 | Year | 06 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000020176
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |