Unique ID issued by UMIN | UMIN000016984 |
---|---|
Receipt number | R000019512 |
Scientific Title | Study for genetic susceptibility to pancreatic cancer |
Date of disclosure of the study information | 2015/04/01 |
Last modified on | 2019/05/15 13:59:59 |
Study for genetic susceptibility to pancreatic cancer
Study for genetic susceptibility to pancreatic cancer
Study for genetic susceptibility to pancreatic cancer
Study for genetic susceptibility to pancreatic cancer
Japan | North America |
pancreatic cancer
Gastroenterology | Laboratory medicine | Adult |
Malignancy
YES
The aim of this study is to identify putative susceptibility gene(s) and the risk of developing pancreatic cancer in Japanese population.
Others
To evaluate pattern of mutation, gene expression and epigenetic alterations unique to young onset (and other subsets of) pancreatic cancer.
Not applicable
Whole-exome sequencing using genomic DNA isolated from saliva, blood and the tissue
Histopathological analysis and somatic mutation, gene expression and methylation analysis using the resected specimens
Observational
20 | years-old | <= |
50 | years-old | > |
Male and Female
For saliva and blood collection:
Patients and volunteers who have given written informed consent
Pancreatic cancer group:
1.Age between 20 and 49
2.Cases with histologically confirmed pancreatic ductal adenocarcinoma
Control group:
1.Age older than 80
2.Healthy volunteers who have no the medical history of cancers and pre-malignant neoplasms.
For tumor tissue collection:
1.Age older than 20
2.Cases with histologically confirmed pancreatic ductal adenocarcinoma
3.Available surgically resected tissue (formalin fixed paraffin embedded block) from pancreatic cancer
Cases with neuroendocrine tumor
100
1st name | Yusuke |
Middle name | |
Last name | Mizukami |
Center for Clinical and Biomedical Research, Sapporo Higashi Tokushukai Hospital
Division of Cancer Research
065-0033
14-3-1 Kita 33-jo Higashi, Higashi-ku, Sapporo, Hokkaido
011-722-1110
ymizu_ccbr@tohtoku.jp
1st name | Yusuke |
Middle name | |
Last name | Mizukami |
Center for Clinical and Biomedical Research, Sapporo Higashi Tokushukai Hospital
Division of Cancer Research
065-0033
14-3-1 Kita 33-jo Higashi, Higashi-ku, Sapporo, Hokkaido
011-722-1110
ymizu_ccbr@tohtoku.jp
Center for Clinical and Biomedical Research, Sapporo Higashi Tokushukai Hospital
Japan Society for the Promotion of Science
Japanese Governmental office
Japan, USA
Shonan Kamakura General Hospital
Chiba Tokushukai Hospital
Teine Keijinkai Hospital
Shibetsu City Hospital
Chiba-Nishi General Hospital
Uji Tokushukai Medical Center
Massachusetts General Hospital
Asahikawa Medical University
American College of Gastroenterology
Self funding
N/A
N/A
N/A
N/A
NO
医療法人 徳洲会 札幌東徳洲会病院付属臨床研究センター
2015 | Year | 04 | Month | 01 | Day |
Unpublished
Completed
2014 | Year | 10 | Month | 02 | Day |
2014 | Year | 10 | Month | 02 | Day |
2014 | Year | 11 | Month | 01 | Day |
2018 | Year | 03 | Month | 31 | Day |
none
2015 | Year | 03 | Month | 31 | Day |
2019 | Year | 05 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000019512