Unique ID issued by UMIN | UMIN000015660 |
---|---|
Receipt number | R000018205 |
Scientific Title | Drug therapies in older patients with glucocorticoid induced osteoporosis |
Date of disclosure of the study information | 2014/11/11 |
Last modified on | 2017/05/13 12:59:06 |
Drug therapies in older patients with glucocorticoid induced osteoporosis
Drug therapies in older patients with glucocorticoid induced osteoporosis
Drug therapies in older patients with glucocorticoid induced osteoporosis
Drug therapies in older patients with glucocorticoid induced osteoporosis
Japan |
glucocorticoid induced osteoporosis
Clinical immunology |
Others
NO
To compare proportions of vertebral fracture between bisphosphonate monotherapy and combination of bisphosphonate and vitamin D in older (>65y) patients with collagen diseases and glucocorticoid induced osteoporosis
Efficacy
proportions of symptomatic vertebral fracture
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
NO
NO
Institution is not considered as adjustment factor.
NO
Central registration
2
Treatment
Medicine |
alendronate sodium
alendronate sodium + activated vitamin D
65 | years-old | <= |
Not applicable |
Male and Female
1. Age >65y
2. Receiving glucocorticoid for more than 3 months or planed to be received for more than 3 months
3. Starting prednisolone wiht more than 10mg /day
1. eGFR<35ml/min or Cre<1.5mg/ml
2. Past history of urinary tract stone
3. Hyper- or hypoparathyroidism
4. Hyper- or hypothyroidism
5. Contraindication of alendronate or vitamin D
6. Warfarinization
7. Other conditions that an investigator assess as inappropriate
8.
200
1st name | |
Middle name | |
Last name | Takao Sugiyama |
Shimosizu Hospital
Rheumatology
Shikawatashi 934-5, Yotsukaido City, Chiba, Japan
043-422-2511
sugiyama@simosizu2.hosp.go.jp
1st name | |
Middle name | |
Last name | Kei Ikeda |
Chiba University Hospital
Allergy and Clinical Immunology
Inohana 1-8-1, Chiba City, Chiba, Japan
043-222-7171
K.Ikeda@faculty.chiba-u.jp
Shimosizu Hospital
Investigators Group for Glucocorticoid Induced Osteoporosis
Other
NO
2014 | Year | 11 | Month | 11 | Day |
Unpublished
Terminated
2010 | Year | 09 | Month | 27 | Day |
2010 | Year | 11 | Month | 01 | Day |
2014 | Year | 11 | Month | 11 | Day |
2017 | Year | 05 | Month | 13 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000018205
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