Unique ID issued by UMIN | UMIN000015334 |
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Receipt number | R000017825 |
Scientific Title | Analgesic effect of intravenous acetaminophen and flurbiprofen after elective breast surgery |
Date of disclosure of the study information | 2014/10/03 |
Last modified on | 2015/10/12 20:43:40 |
Analgesic effect of intravenous acetaminophen and flurbiprofen after elective breast surgery
Analgesic effect of intravenous acetaminophen and flurbiprofen after elective breast surgery
Analgesic effect of intravenous acetaminophen and flurbiprofen after elective breast surgery
Analgesic effect of intravenous acetaminophen and flurbiprofen after elective breast surgery
Japan |
breast cancer
Breast surgery |
Malignancy
NO
The aim of our study is to compare the analgesic effects of an intravenous acetaminophen and flurbiprofen, an intravenous non-steroidal anti-inflammatory drugs, after elective breast surgeries.
Efficacy
Postoperative pain evaluation performed by visual analog scale (VAS) after 3 hours, 6 hours and 24 hours postoperatively.
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Active
NO
NO
Institution is not considered as adjustment factor.
YES
Numbered container method
2
Treatment
Medicine |
intravenous acetaminophen (1000mg) injection 15minutes before the end of surgery, and after 6 hours, 12hours postoperatively
flurbiprofen (50mg) injection 15minutes before the end of surgery, and after 6 hours, 12hours postoperatively
20 | years-old | <= |
Not applicable |
Female
a patient for elective partial mastectomy
a 50-65 kilograms adult
past history of peptic ulcer
eGFR under 60 ml/min
an allergy to propionic acid-based NSAIDs
an allergy to acetaminophen
a pregnant woman
past history of Aspirin-induced asthma
liver cirrhosis
contraindication to propofol
40
1st name | |
Middle name | |
Last name | Tatsuo Yamamoto |
Kumamoto university hospital
Department of anesthesiology
1-1-1 Honjo, Chuo-ku, Kumamoto
096-373-5275
yamyam@kumamoto-u.ac.jp
1st name | |
Middle name | |
Last name | Takahiro Nonaka |
Kumamoto university hospital
Department of anesthesiology
1-1-1 Honjo, Chuo-ku, Kumamoto
096-373-5275
end_of_uruma@yahoo.co.jp
Department of anesthesiology, Kumamoto university
none
Self funding
NO
2014 | Year | 10 | Month | 03 | Day |
Unpublished
Completed
2014 | Year | 10 | Month | 01 | Day |
2014 | Year | 10 | Month | 03 | Day |
2015 | Year | 07 | Month | 09 | Day |
2014 | Year | 10 | Month | 03 | Day |
2015 | Year | 10 | Month | 12 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000017825
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