Unique ID issued by UMIN | UMIN000015314 |
---|---|
Receipt number | R000017798 |
Scientific Title | The assessment of median nerve elasticity in patients with rheumatoid arthritis by using elastosonography (multicenter clinical study) |
Date of disclosure of the study information | 2014/10/01 |
Last modified on | 2020/03/16 18:42:34 |
The assessment of median nerve elasticity in patients with rheumatoid arthritis by using elastosonography (multicenter clinical study)
The assessment of median nerve elasticity in patients with rheumatoid arthritis
The assessment of median nerve elasticity in patients with rheumatoid arthritis by using elastosonography (multicenter clinical study)
The assessment of median nerve elasticity in patients with rheumatoid arthritis
Japan |
rheumatoid arthritis
Orthopedics |
Others
NO
The aim of this study is to measure the median nerve stiffness by using elastosonography at the carpal tunnel level and check subclinical damage of the median nerve. The median nerve stiffness of patients with rheumatoid arthritis is compared to the stiffness of healthy control.
Others
This study is cross sectional study without any intervention.
Exploratory
Pragmatic
Not applicable
To compare the median nerve stiffness of patients with rheumatoid arthritis with healthy controls
To compare the median nerve cross sectional area of patients with rheumatoid arthritis with healthy controls
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1)1.patients with rheumatoid arthritis, 2.healthy controls
1)both men and women who are over 20 years old
3)participants who accepted to join our study
1)participants who have a possibility of secondary carpal tunnel syndrome (diabetes mellitus, acute trauma, pregnancy, hypothyroidism, hyperthyroidism, rheumatic disease except for rheumatoid arthritis)
2)double crush syndrome patients (with cervical spondylosis)
3)cervical spondylotic myelopathy patients
4)poly myelopathy patients
5)patients who have previous fracture of wrist
6)patients who have previous surgery of wrist
7)participants who are considered to join this study is not appropriated
300
1st name | Tadashi |
Middle name | |
Last name | Okano |
Osaka city university
Orthopedic surgery
545-8585
1-4-3 Asahimachi, Abenoku, Osaka city, Osaka
06-6645-3851
ma1sa3ru@med.osaka-cu.ac.jp
1st name | Tadashi |
Middle name | |
Last name | Okano |
Osaka city university
Orthopedic surgery
545-8585
1-4-3 Asahimachi, Abenoku, Osaka city, Osaka
06-6645-3851
ma1sa3ru@med.osaka-cu.ac.jp
Osaka city university, Orthopedic surgery
None
Self funding
Osaka city university
1-2-7 Asahimachi, Abenoku, Osaka city, Osaka
06-6645-3435
ethics@med.osaka-cu.ac.jp.
NO
大阪市立大学大学院医学研究科
2014 | Year | 10 | Month | 01 | Day |
http://www.med.osaka-cu.ac.jp/orthoped/research/
Published
https://www.tandfonline.com/doi/abs/10.1080/14397595.2019.1602914?journalCode=imor20
312
The nerve stiffness in patients with RA measured by ultrasound real-time tissue elastography was higher than without RA. Inflammatory condition of the flexor tendon and wrist joint in patients with RA may generate fibrotic changes in the median nerve.
2020 | Year | 03 | Month | 16 | Day |
402 hands of 201 RA group and 222 hands of 111 non-RA group
Provide informed consent directly to the selected patients and have them give their consent in a written consent form.
In this study, only ultrasound examination was performed and no specific adverse events were reported.
Ultrasonography was performed to evaluate the circumference, cross-sectional area (CSA) and strain ratio as an elasticity of the median nerve at the inlet level of the carpal tunnel and the proximal portion of the carpal tunnel inlet.
Completed
2014 | Year | 04 | Month | 01 | Day |
2014 | Year | 03 | Month | 05 | Day |
2014 | Year | 10 | Month | 01 | Day |
2017 | Year | 03 | Month | 31 | Day |
case-control sumpling
2014 | Year | 10 | Month | 01 | Day |
2020 | Year | 03 | Month | 16 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000017798
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |