Unique ID issued by UMIN | UMIN000015198 |
---|---|
Receipt number | R000017665 |
Scientific Title | The effect of pre-landiololtreatment on ischemic reperfusion injury in acute myocardial infarction trial |
Date of disclosure of the study information | 2014/09/17 |
Last modified on | 2018/06/28 09:26:58 |
The effect of pre-landiololtreatment on ischemic reperfusion injury in acute myocardial infarction trial
PROTECTION trial
The effect of pre-landiololtreatment on ischemic reperfusion injury in acute myocardial infarction trial
PROTECTION trial
Japan |
acute myocardial infarction
Cardiology |
Others
NO
To evaluate the effect of landiolol on ischemic reperfusion in patients with acute myocardial infarction
Efficacy
Myocardial salvage index determined with MRI
Interventional
Parallel
Randomized
Open -but assessor(s) are blinded
Placebo
2
Treatment
Medicine |
Intravenous landiolol injection
saline injection
20 | years-old | <= |
Not applicable |
Male and Female
patients with acute myocardial infarction within 12 hours after onset
(a) Killip class III or IV
(b) systolic BP less than 120 mmHg
(c)PR duration over 240 ms
(d)AV block (grade II ro III)
(e)heart rate less than 60bpm
(f)Patients receiving oral beta blockers
(g) LVEF less than 30%
(h) Patients having allergy against landiolol and/or nitrates
(i)patients receiving any unapproved drugs for clinical study within 6 months
(j)Pregnant
(k)patients having any disease which is less than 12 months of prognosis
(l)Diabetic ketoacidosis or metabolic ketoacidosis
(m)Prior myocadial infarction
(n)patients wiht pacemaker or ICD
92
1st name | |
Middle name | |
Last name | Hiroshi Ito |
Okayama University
Cardiovascular Medicine
2-5-1, Shikata-cho, Kita-ku, Okayama
086-235-7351
itomd@md.okayama-u.ac.jp
1st name | |
Middle name | |
Last name | Toru Miyoshi |
Okayama University
Cardiovascular Medicine
2-5-1 Shikada-cho Kita-ku Okayama
086-235-7351
miyoshit@cc.okayama-u.ac.jp
Department of Cardiovascular Medicine, Okayama Univeersity
Department of Cardiovascular Medicine, Okayama Univeersity
NO
2014 | Year | 09 | Month | 17 | Day |
Unpublished
Completed
2014 | Year | 06 | Month | 01 | Day |
2014 | Year | 06 | Month | 01 | Day |
2014 | Year | 09 | Month | 17 | Day |
2018 | Year | 06 | Month | 28 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000017665
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |