Unique ID issued by UMIN | UMIN000014990 |
---|---|
Receipt number | R000017269 |
Scientific Title | Fukui cohort study for early Alzheimer disease |
Date of disclosure of the study information | 2014/09/10 |
Last modified on | 2024/09/05 12:47:57 |
Fukui cohort study for early Alzheimer disease
Fukui cohort for EAD
Fukui cohort study for early Alzheimer disease
Fukui cohort for EAD
Japan |
Healthy subjects and patients with MCI
Neurology | Geriatrics | Psychiatry |
Laboratory medicine | Adult |
Others
NO
To prevent AD era, diagnosis method for EAD should be established.
Efficacy
Follow-up study for the participants using brain images and MMSE/HDS-R
Interventional
Parallel
Non-randomized
Open -no one is blinded
No treatment
2
Diagnosis
Other |
PiB PET PiB-PET positive
PiB-PET negative
50 | years-old | <= |
90 | years-old | > |
Male and Female
Pisitive subject by CCI (CCI>16)
Patients with Alzheimer's disease or other dementia.
300
1st name | Hidehiko |
Middle name | |
Last name | Okazawa |
University of Fukui
Biomedical Imaging Research Center
910-1193
23-3 Matsuoka-SHimoaizuki, Eiheiji-cho
0776-61-8491
okazawa@u-fukui.ac.jp
1st name | Hidehiko |
Middle name | |
Last name | Okazawa |
University of Fukui
Biomedical Imaging Research Center
910-1193
23-3 Matsuoka-SHimoaizuki, Eiheiji-cho
0776-61-8491
bircfukui@gmail.com
Biomedical Imaging Research Center, University of Fukui
Biomedical Imaging Research Center, University of Fukui
Self funding
Ethics Committee
23-3 Matsuoka-Shimoaizuki, Eiheiji-cho, Fukui
0776-61-8491
okazawa@u-fukui.ac.jp
NO
福井大学
2014 | Year | 09 | Month | 10 | Day |
Unpublished
Unpublished
https://www.mdpi.com/2076-3921/11/5/1022
20
Preliminary data and results were published in the journal of the Antioxidants.
Okazawa H, Ikawa M, et al. Cerebral oxidative stress in early Alzheimer's disease evaluated by 64Cu-ATSM PET/MRI: A preliminary study. Antioxidants 2022, 11(5), 2022.
2022 | Year | 09 | Month | 05 | Day |
Patients with MCI - early phase dementia in their 45-89 years of age, and healthy volunteers in the same age.
Participants undergo clinical interview, MMSE, and PET/MRI scans with [C-11]PiB, [F-18]MK6240, [Cu-64]ATSM, etc. They are followed up for 1-2 years, and undergo the same exams again.
No adverse event.
Participants will be divided into 2 groups of positive/negative amyloid and tau, and compared with various other biomarkers. Changes after follow-up will be also evaluated.
Open public recruiting
2014 | Year | 07 | Month | 30 | Day |
2014 | Year | 08 | Month | 06 | Day |
2014 | Year | 08 | Month | 27 | Day |
2026 | Year | 03 | Month | 31 | Day |
2026 | Year | 03 | Month | 31 | Day |
2014 | Year | 08 | Month | 29 | Day |
2024 | Year | 09 | Month | 05 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000017269